SDO63167.1 protein (Nakamurella panacisegetis)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

SDO63167.1

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain. (434 aa)

Predicted Functional Partners:

ddl-2

0.939

SDP05675.1

0.833

SDO41179.1

0.766

SDO84001.1

0.746

SDO26059.1

0.698

SDO63238.1

0.514

SDO63261.1

0.514

SDO63295.1

0.514

SDO65351.1

0.506

SDO91534.1

0.506

Your Current Organism:

Nakamurella panacisegetis

NCBI taxonomy Id: 1090615
Other names: CECT 7604, DSM 26919, KCTC 19426, N. panacisegetis, Nakamurella panacisegetis Kim et al. 2012, Nakamurella sp. P4-7, strain P4-7

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDO26059.1	SDO41179.1	SAMN04515671_0343	SAMN04515671_0857	2-oxoglutarate decarboxylase.	4-hydroxymandelate oxidase.	0.654
SDO26059.1	SDO63167.1	SAMN04515671_0343	SAMN04515671_1538	2-oxoglutarate decarboxylase.	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain.	0.698
SDO26059.1	SDO84001.1	SAMN04515671_0343	SAMN04515671_2103	2-oxoglutarate decarboxylase.	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase.	0.654
SDO41179.1	SDO26059.1	SAMN04515671_0857	SAMN04515671_0343	4-hydroxymandelate oxidase.	2-oxoglutarate decarboxylase.	0.654
SDO41179.1	SDO63167.1	SAMN04515671_0857	SAMN04515671_1538	4-hydroxymandelate oxidase.	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain.	0.766
SDO41179.1	SDP05675.1	SAMN04515671_0857	SAMN04515671_2822	4-hydroxymandelate oxidase.	4-hydroxyphenylpyruvate dioxygenase.	0.790
SDO63167.1	SDO26059.1	SAMN04515671_1538	SAMN04515671_0343	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain.	2-oxoglutarate decarboxylase.	0.698
SDO63167.1	SDO41179.1	SAMN04515671_1538	SAMN04515671_0857	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain.	4-hydroxymandelate oxidase.	0.766
SDO63167.1	SDO63238.1	SAMN04515671_1538	SAMN04515671_1540	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain.	Hypothetical protein.	0.514
SDO63167.1	SDO63261.1	SAMN04515671_1538	SAMN04515671_1541	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain.	Uncharacterized protein YrrD, contains PRC-barrel domain.	0.514
SDO63167.1	SDO63295.1	SAMN04515671_1538	SAMN04515671_1542	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain.	PRC-barrel domain-containing protein.	0.514
SDO63167.1	SDO65351.1	SAMN04515671_1538	SAMN04515671_1597	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain.	enoyl-CoA hydratase.	0.506
SDO63167.1	SDO84001.1	SAMN04515671_1538	SAMN04515671_2103	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain.	FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase.	0.746
SDO63167.1	SDO91534.1	SAMN04515671_1538	SAMN04515671_2346	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain.	Enoyl-CoA hydratase/carnithine racemase.	0.506
SDO63167.1	SDP05675.1	SAMN04515671_1538	SAMN04515671_2822	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain.	4-hydroxyphenylpyruvate dioxygenase.	0.833
SDO63167.1	ddl-2	SAMN04515671_1538	SAMN04515671_1539	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain.	D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.	0.939
SDO63238.1	SDO63167.1	SAMN04515671_1540	SAMN04515671_1538	Hypothetical protein.	DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain.	0.514
SDO63238.1	SDO63261.1	SAMN04515671_1540	SAMN04515671_1541	Hypothetical protein.	Uncharacterized protein YrrD, contains PRC-barrel domain.	0.773
SDO63238.1	SDO63295.1	SAMN04515671_1540	SAMN04515671_1542	Hypothetical protein.	PRC-barrel domain-containing protein.	0.773
SDO63238.1	ddl-2	SAMN04515671_1540	SAMN04515671_1539	Hypothetical protein.	D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.	0.520

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Network Stats

number of nodes:

11

number of edges:

20

average node degree:

3.64

avg. local clustering coefficient:

0.841

expected number of edges:

15

PPI enrichment p-value:

0.103

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005975

Carbohydrate metabolic process

9 of 207

1.14

1.4

6.82e-07

GO:0005976

Polysaccharide metabolic process

5 of 57

1.45

1.36

0.00040

GO:0009225

Nucleotide-sugar metabolic process

3 of 18

1.73

1.08

0.0064

GO:0034637

Cellular carbohydrate biosynthetic process

4 of 46

1.44

1.06

0.0036

GO:0016051

Carbohydrate biosynthetic process

5 of 90

1.25

0.99

0.0023

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016779

Nucleotidyltransferase activity

5 of 51

1.5

1.45

0.00026

GO:0016868

Intramolecular transferase activity, phosphotransferases

2 of 5

2.11

0.73

0.0446

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2438

O-Antigen nucleotide sugar biosynthesis, and Alpha-D-phosphohexomutase, C-terminal

5 of 16

2.0

2.98

3.33e-07

CL:2431

Mixed, incl. Polysaccharide metabolic process, and O-Antigen nucleotide sugar biosynthesis

9 of 83

1.54

2.83

1.64e-10

CL:2439

O-Antigen nucleotide sugar biosynthesis

4 of 8

2.2

2.8

2.57e-06

CL:2434

Mixed, incl. O-Antigen nucleotide sugar biosynthesis, and Polysaccharide biosynthetic process

6 of 50

1.58

2.25

7.27e-07

CL:2565

Glucan metabolic process, and Disaccharide metabolic process

3 of 10

1.98

1.68

0.00043

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00541

O-Antigen nucleotide sugar biosynthesis

6 of 22

1.94

3.56

4.04e-09

map00520

Amino sugar and nucleotide sugar metabolism

8 of 52

1.69

3.36

8.78e-11

map00500

Starch and sucrose metabolism

6 of 33

1.76

2.98

2.30e-08

map00052

Galactose metabolism

3 of 22

1.64

1.32

0.0013

map00521

Streptomycin biosynthesis

2 of 17

1.57

0.77

0.0265

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0548

Nucleotidyltransferase

4 of 42

1.48

1.19

0.0017

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF12804

MobA-like NTP transferase domain

4 of 9

2.15

2.36

2.07e-05

PF02880

Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III

2 of 3

2.33

0.87

0.0251

PF02879

Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II

2 of 3

2.33

0.87

0.0251

PF02878

Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I

2 of 3

2.33

0.87

0.0251

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR005835

Nucleotidyl transferase domain

4 of 6

2.33

2.65

7.64e-06

IPR029044

Nucleotide-diphospho-sugar transferases

6 of 37

1.71

2.38

1.45e-06

IPR036900

Alpha-D-phosphohexomutase, C-terminal domain superfamily

2 of 3

2.33

0.75

0.0419

IPR016066

Alpha-D-phosphohexomutase, conserved site

2 of 3

2.33

0.75

0.0419

IPR016055

Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III

2 of 3

2.33

0.75

0.0419

(more ...)

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