node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDO26245.1 | prcA | SAMN04515671_0351 | SAMN04515671_3721 | ATPase family associated with various cellular activities (AAA). | Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.962 |
SDO26245.1 | prcB | SAMN04515671_0351 | SAMN04515671_3720 | ATPase family associated with various cellular activities (AAA). | Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.962 |
SDO26245.1 | pup | SAMN04515671_0351 | SAMN04515671_3719 | ATPase family associated with various cellular activities (AAA). | Prokaryotic ubiquitin-like protein Pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. | 0.907 |
SDO50163.1 | SDP32130.1 | SAMN04515671_1140 | SAMN04515671_3718 | Protein of unknown function. | Proteasome accessory factor A. | 0.613 |
SDO50163.1 | arc | SAMN04515671_1140 | SAMN04515671_3715 | Protein of unknown function. | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.800 |
SDO50163.1 | pafA | SAMN04515671_1140 | SAMN04515671_3731 | Protein of unknown function. | Proteasome accessory factor A; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.705 |
SDO50163.1 | prcA | SAMN04515671_1140 | SAMN04515671_3721 | Protein of unknown function. | Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.999 |
SDO50163.1 | prcB | SAMN04515671_1140 | SAMN04515671_3720 | Protein of unknown function. | Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.977 |
SDO50163.1 | pup | SAMN04515671_1140 | SAMN04515671_3719 | Protein of unknown function. | Prokaryotic ubiquitin-like protein Pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. | 0.687 |
SDP32130.1 | SDO50163.1 | SAMN04515671_3718 | SAMN04515671_1140 | Proteasome accessory factor A. | Protein of unknown function. | 0.613 |
SDP32130.1 | arc | SAMN04515671_3718 | SAMN04515671_3715 | Proteasome accessory factor A. | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.941 |
SDP32130.1 | pafA | SAMN04515671_3718 | SAMN04515671_3731 | Proteasome accessory factor A. | Proteasome accessory factor A; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.445 |
SDP32130.1 | prcA | SAMN04515671_3718 | SAMN04515671_3721 | Proteasome accessory factor A. | Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.925 |
SDP32130.1 | prcB | SAMN04515671_3718 | SAMN04515671_3720 | Proteasome accessory factor A. | Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.933 |
SDP32130.1 | pup | SAMN04515671_3718 | SAMN04515671_3719 | Proteasome accessory factor A. | Prokaryotic ubiquitin-like protein Pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. | 0.926 |
SDP40888.1 | SDP40911.1 | SAMN04515671_4094 | SAMN04515671_4095 | ABC-2 type transport system permease protein. | Cytochrome c oxidase assembly protein subunit 15. | 0.968 |
SDP40888.1 | SDP49074.1 | SAMN04515671_4094 | SAMN04515671_4469 | ABC-2 type transport system permease protein. | Predicted dithiol-disulfide isomerase, DsbA family. | 0.444 |
SDP40888.1 | pafA | SAMN04515671_4094 | SAMN04515671_3731 | ABC-2 type transport system permease protein. | Proteasome accessory factor A; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.433 |
SDP40888.1 | pup | SAMN04515671_4094 | SAMN04515671_3719 | ABC-2 type transport system permease protein. | Prokaryotic ubiquitin-like protein Pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. | 0.597 |
SDP40911.1 | SDP40888.1 | SAMN04515671_4095 | SAMN04515671_4094 | Cytochrome c oxidase assembly protein subunit 15. | ABC-2 type transport system permease protein. | 0.968 |