relA_1 protein (Rickettsia monacensis) - STRING interaction network

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Score

relA_1

GTP pyrophosphokinase. (201 aa)

Predicted Functional Partners:

rsh_3

0.881

rsh_1

0.774

rsh_5

0.773

rplF

0.723

rplB

0.723

rpsE

0.722

rpsF

0.718

rplT

0.716

rplX

0.716

rplJ

0.714

Your Current Organism:

Rickettsia monacensis

NCBI taxonomy Id: 109232
Other names: R. monacensis, Rickettsia sp. IrR/Munich, strain IrR/Munich

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
relA_1	rplB	RMONA_00210	RMONA_08205	GTP pyrophosphokinase.	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.723
relA_1	rplF	RMONA_00210	RMONA_08145	GTP pyrophosphokinase.	50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.	0.723
relA_1	rplJ	RMONA_00210	RMONA_02980	GTP pyrophosphokinase.	50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	0.714
relA_1	rplT	RMONA_00210	RMONA_07860	GTP pyrophosphokinase.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.716
relA_1	rplX	RMONA_00210	RMONA_08165	GTP pyrophosphokinase.	50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.	0.716
relA_1	rpsE	RMONA_00210	RMONA_08135	GTP pyrophosphokinase.	30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	0.722
relA_1	rpsF	RMONA_00210	RMONA_02110	GTP pyrophosphokinase.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.718
relA_1	rsh_1	RMONA_00210	RMONA_03705	GTP pyrophosphokinase.	GTP pyrophosphokinase rsh.	0.774
relA_1	rsh_3	RMONA_00210	RMONA_04825	GTP pyrophosphokinase.	GTP pyrophosphokinase rsh.	0.881
relA_1	rsh_5	RMONA_00210	RMONA_05525	GTP pyrophosphokinase.	GTP pyrophosphokinase rsh.	0.773
rplB	relA_1	RMONA_08205	RMONA_00210	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	GTP pyrophosphokinase.	0.723
rplB	rplF	RMONA_08205	RMONA_08145	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.	0.999
rplB	rplJ	RMONA_08205	RMONA_02980	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.	0.999
rplB	rplT	RMONA_08205	RMONA_07860	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.999
rplB	rplX	RMONA_08205	RMONA_08165	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.	0.999
rplB	rpsE	RMONA_08205	RMONA_08135	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	0.999
rplB	rpsF	RMONA_08205	RMONA_02110	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.999
rplB	rsh_1	RMONA_08205	RMONA_03705	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	GTP pyrophosphokinase rsh.	0.532
rplB	rsh_3	RMONA_08205	RMONA_04825	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	GTP pyrophosphokinase rsh.	0.532
rplB	rsh_5	RMONA_08205	RMONA_05525	50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	GTP pyrophosphokinase rsh.	0.532