Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
virB4_1Type IV secretion system protein virB4. (810 aa)    
Predicted Functional Partners:
CEO16718.1
Type IV secretory pathway, VirB3-like protein.
 
 
 0.993
CEO17946.1
Type IV secretion system protein virB10.
 
 
 0.985
virB8_1
Type IV secretion system protein VirB8.
 
 
 0.975
CEO16722.1
Type IV secretion system protein VirB6.
 
 
 0.973
CEO16724.1
Type IV secretion system protein VirB6.
 
 
 0.973
CEO16723.1
Type IV secretion system protein VirB6.
 
 
 0.935
virB9_1
Type IV secretion system protein virB9 precursor.
 
  
 0.931
virB9_2
Type IV secretion system protein virB9 precursor.
 
  
 0.931
virB4_2
Type IV secretion system protein virB4.
  
  
 
0.927
CEO16720.1
Type IV secretion system protein VirB6.
  
 
 0.905
Your Current Organism:
Rickettsia monacensis
NCBI taxonomy Id: 109232
Other names: R. monacensis, Rickettsia sp. IrR/Munich, strain IrR/Munich
Server load: low (18%) [HD]