STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kefCGlutathione-regulated potassium-efflux system protein KefC; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (575 aa)    
Predicted Functional Partners:
CEO16693.1
Bacterial SH3 domain protein.
       0.834
rsfS
Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
       0.831
hupA
DNA-binding protein HU 1; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
   
 
 0.739
ihfB
Integration host factor subunit beta; Belongs to the bacterial histone-like protein family.
   
 
 0.739
degP1
Putative periplasmic serine endoprotease DegP-like precursor.
 
   
 0.688
ybdG
Miniconductance mechanosensitive channel YbdG.
  
  
 0.648
CEO16981.1
Hypothetical protein.
     
 0.643
htrB
Serine protease Do-like HtrB.
     
 0.643
cshA
DEAD-box ATP-dependent RNA helicase CshA.
     
 0.630
uspF
Universal stress protein F.
     
 0.620
Your Current Organism:
Rickettsia monacensis
NCBI taxonomy Id: 109232
Other names: R. monacensis, Rickettsia sp. IrR/Munich, strain IrR/Munich
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.