hemE protein (Rickettsia monacensis) - STRING interaction network

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hemE

Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (346 aa)

Predicted Functional Partners:

hemH

0.993

hemC

0.991

hemF

0.969

CEO16841.1

0.879

hemB

0.858

polA

0.856

gltB

0.654

mnmG

0.650

coaE

0.642

dnaQ

0.620

Your Current Organism:

Rickettsia monacensis

NCBI taxonomy Id: 109232
Other names: R. monacensis, Rickettsia sp. IrR/Munich, strain IrR/Munich

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEO16841.1	coaE	RMONA_02165	RMONA_03260	Hypothetical protein.	Dephospho-CoA kinase; Belongs to the CoaE family.	0.411
CEO16841.1	dnaQ	RMONA_02165	RMONA_03270	Hypothetical protein.	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.403
CEO16841.1	hemC	RMONA_02165	RMONA_04970	Hypothetical protein.	Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.	0.430
CEO16841.1	hemE	RMONA_02165	RMONA_02175	Hypothetical protein.	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	0.879
CEO16841.1	hemF	RMONA_02165	RMONA_02650	Hypothetical protein.	Coproporphyrinogen-III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.	0.964
CEO16841.1	hemH	RMONA_02165	RMONA_02170	Hypothetical protein.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.	0.989
coaE	CEO16841.1	RMONA_03260	RMONA_02165	Dephospho-CoA kinase; Belongs to the CoaE family.	Hypothetical protein.	0.411
coaE	dnaQ	RMONA_03260	RMONA_03270	Dephospho-CoA kinase; Belongs to the CoaE family.	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	0.869
coaE	hemE	RMONA_03260	RMONA_02175	Dephospho-CoA kinase; Belongs to the CoaE family.	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	0.642
coaE	polA	RMONA_03260	RMONA_00495	Dephospho-CoA kinase; Belongs to the CoaE family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.865
dnaQ	CEO16841.1	RMONA_03270	RMONA_02165	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Hypothetical protein.	0.403
dnaQ	coaE	RMONA_03270	RMONA_03260	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Dephospho-CoA kinase; Belongs to the CoaE family.	0.869
dnaQ	hemE	RMONA_03270	RMONA_02175	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	0.620
dnaQ	polA	RMONA_03270	RMONA_00495	DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.843
gltB	hemB	RMONA_02200	RMONA_07160	Glutamate synthase [NADPH] small chain.	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	0.522
gltB	hemE	RMONA_02200	RMONA_02175	Glutamate synthase [NADPH] small chain.	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	0.654
hemB	gltB	RMONA_07160	RMONA_02200	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	Glutamate synthase [NADPH] small chain.	0.522
hemB	hemC	RMONA_07160	RMONA_04970	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.	0.998
hemB	hemE	RMONA_07160	RMONA_02175	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	0.858
hemB	hemF	RMONA_07160	RMONA_02650	Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.	Coproporphyrinogen-III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.	0.656