| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CEO17030.1 | glyA | RMONA_03160 | RMONA_03165 | Putative hydrolase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.592 |
| CEO17030.1 | grxD | RMONA_03160 | RMONA_03155 | Putative hydrolase. | Glutaredoxin-4; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.616 |
| CEO17030.1 | lipA | RMONA_03160 | RMONA_03170 | Putative hydrolase. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.603 |
| CEO17030.1 | tlyC | RMONA_03160 | RMONA_03180 | Putative hydrolase. | Hemolysin C. | 0.559 |
| CEO17030.1 | ybeY | RMONA_03160 | RMONA_03175 | Putative hydrolase. | Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.592 |
| corC | tlyC | RMONA_00145 | RMONA_03180 | Magnesium and cobalt efflux protein CorC. | Hemolysin C. | 0.434 |
| glyA | CEO17030.1 | RMONA_03165 | RMONA_03160 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative hydrolase. | 0.592 |
| glyA | grxD | RMONA_03165 | RMONA_03155 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glutaredoxin-4; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.529 |
| glyA | lipA | RMONA_03165 | RMONA_03170 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.825 |
| glyA | pld_2 | RMONA_03165 | RMONA_05790 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phospholipase D precursor. | 0.581 |
| glyA | tlyC | RMONA_03165 | RMONA_03180 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Hemolysin C. | 0.750 |
| glyA | ybeY | RMONA_03165 | RMONA_03175 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.797 |
| grxD | CEO17030.1 | RMONA_03155 | RMONA_03160 | Glutaredoxin-4; Belongs to the glutaredoxin family. Monothiol subfamily. | Putative hydrolase. | 0.616 |
| grxD | glyA | RMONA_03155 | RMONA_03165 | Glutaredoxin-4; Belongs to the glutaredoxin family. Monothiol subfamily. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.529 |
| grxD | lipA | RMONA_03155 | RMONA_03170 | Glutaredoxin-4; Belongs to the glutaredoxin family. Monothiol subfamily. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.630 |
| grxD | tlyC | RMONA_03155 | RMONA_03180 | Glutaredoxin-4; Belongs to the glutaredoxin family. Monothiol subfamily. | Hemolysin C. | 0.454 |
| grxD | ybeY | RMONA_03155 | RMONA_03175 | Glutaredoxin-4; Belongs to the glutaredoxin family. Monothiol subfamily. | Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.479 |
| lipA | CEO17030.1 | RMONA_03170 | RMONA_03160 | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Putative hydrolase. | 0.603 |
| lipA | glyA | RMONA_03170 | RMONA_03165 | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.825 |
| lipA | grxD | RMONA_03170 | RMONA_03155 | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Glutaredoxin-4; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.630 |