rpiB protein (Rickettsia monacensis) - STRING interaction network

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Score

rpiB

Putative ribose-5-phosphate isomerase B. (144 aa)

Predicted Functional Partners:

glyA

0.943

ubiG_4

0.862

prmC_1

0.728

tme

0.649

thyX

0.620

nlpD

0.570

acoB

0.564

atpD

0.562

CEO17317.1

0.560

CEO17318.1

0.560

Your Current Organism:

Rickettsia monacensis

NCBI taxonomy Id: 109232
Other names: R. monacensis, Rickettsia sp. IrR/Munich, strain IrR/Munich

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEO17317.1	CEO17318.1	RMONA_04660	RMONA_04665	WLM domain protein.	Hypothetical protein.	0.773
CEO17317.1	nlpD	RMONA_04660	RMONA_04655	WLM domain protein.	Murein hydrolase activator NlpD precursor.	0.773
CEO17317.1	rpiB	RMONA_04660	RMONA_04650	WLM domain protein.	Putative ribose-5-phosphate isomerase B.	0.560
CEO17317.1	thyX	RMONA_04660	RMONA_04670	WLM domain protein.	Thymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.	0.774
CEO17318.1	CEO17317.1	RMONA_04665	RMONA_04660	Hypothetical protein.	WLM domain protein.	0.773
CEO17318.1	nlpD	RMONA_04665	RMONA_04655	Hypothetical protein.	Murein hydrolase activator NlpD precursor.	0.773
CEO17318.1	rpiB	RMONA_04665	RMONA_04650	Hypothetical protein.	Putative ribose-5-phosphate isomerase B.	0.560
CEO17318.1	thyX	RMONA_04665	RMONA_04670	Hypothetical protein.	Thymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.	0.773
acoB	atpD	RMONA_04135	RMONA_01050	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.	0.714
acoB	glyA	RMONA_04135	RMONA_03165	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.654
acoB	rpiB	RMONA_04135	RMONA_04650	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Putative ribose-5-phosphate isomerase B.	0.564
acoB	tme	RMONA_04135	RMONA_05480	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	NADP-dependent malic enzyme.	0.999
atpD	acoB	RMONA_01050	RMONA_04135	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.714
atpD	prmC_1	RMONA_01050	RMONA_01860	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.	Release factor glutamine methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.	0.631
atpD	rpiB	RMONA_01050	RMONA_04650	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.	Putative ribose-5-phosphate isomerase B.	0.562
atpD	tme	RMONA_01050	RMONA_05480	ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.	NADP-dependent malic enzyme.	0.615
glyA	acoB	RMONA_03165	RMONA_04135	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.654
glyA	rpiB	RMONA_03165	RMONA_04650	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Putative ribose-5-phosphate isomerase B.	0.943
glyA	thyX	RMONA_03165	RMONA_04670	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Thymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.	0.949
glyA	tme	RMONA_03165	RMONA_05480	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	NADP-dependent malic enzyme.	0.722