STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoVDStage V sporulation protein D. (593 aa)    
Predicted Functional Partners:
mrdB
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 0.992
ftsI
Peptidoglycan synthase FtsI.
 
  
0.940
mreC
Cell shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.936
ftsW
Lipid II flippase FtsW; Belongs to the SEDS family.
 
 0.925
mreB
Rod shape-determining protein MreB.
 
 
 
 0.920
ftsQ
Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
  
 
 0.875
CEO17154.1
Hypothetical protein.
  
 
 0.855
CEO17577.1
Hypothetical protein.
  
  
 0.836
murE
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
  
 0.783
mrcA
Penicillin-binding protein 1A.
 
 
 
0.735
Your Current Organism:
Rickettsia monacensis
NCBI taxonomy Id: 109232
Other names: R. monacensis, Rickettsia sp. IrR/Munich, strain IrR/Munich
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.