Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CEO17616.1FKBP-type peptidyl-prolyl cis-trans isomerase. (329 aa)    
Predicted Functional Partners:
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.
   
 0.912
bamA
Outer membrane protein assembly factor BamA precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
   
 
 0.873
bamD
Outer membrane protein assembly factor BamD precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
   
 
 0.842
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
   0.808
bamB
Outer membrane protein assembly factor BamB precursor.
   
 
 0.782
lysC
Aspartokinase 2; Belongs to the aspartokinase family.
   
   0.779
CEO17615.1
Hypothetical protein.
       0.773
CEO17291.1
Hypothetical protein; COQ9.
  
   0.725
hscA
Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
   
 0.718
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.718
Your Current Organism:
Rickettsia monacensis
NCBI taxonomy Id: 109232
Other names: R. monacensis, Rickettsia sp. IrR/Munich, strain IrR/Munich
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