IER5L protein (Hippocampus comes) - STRING interaction network

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

IER5L

Immediate early response 5-like. (283 aa)

Predicted Functional Partners:

naa25

0.593

phax

0.586

cunh10orf71

0.585

get3

0.579

tm9sf4

0.527

psmc5

0.407

Gen1

0.407

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Gen1	IER5L	ENSHCOP00000024625	ENSHCOP00000001417	Uncharacterized protein.	Immediate early response 5-like.	0.407
Gen1	naa25	ENSHCOP00000024625	ENSHCOP00000003522	Uncharacterized protein.	N(alpha)-acetyltransferase 25, NatB auxiliary subunit.	0.405
IER5L	Gen1	ENSHCOP00000001417	ENSHCOP00000024625	Immediate early response 5-like.	Uncharacterized protein.	0.407
IER5L	cunh10orf71	ENSHCOP00000001417	ENSHCOP00000016312	Immediate early response 5-like.	DUF4585 domain-containing protein.	0.585
IER5L	get3	ENSHCOP00000001417	ENSHCOP00000016046	Immediate early response 5-like.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.579
IER5L	naa25	ENSHCOP00000001417	ENSHCOP00000003522	Immediate early response 5-like.	N(alpha)-acetyltransferase 25, NatB auxiliary subunit.	0.593
IER5L	phax	ENSHCOP00000001417	ENSHCOP00000021966	Immediate early response 5-like.	Phosphorylated adaptor for RNA export.	0.586
IER5L	psmc5	ENSHCOP00000001417	ENSHCOP00000014246	Immediate early response 5-like.	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.	0.407
IER5L	tm9sf4	ENSHCOP00000001417	ENSHCOP00000003242	Immediate early response 5-like.	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.	0.527
cunh10orf71	IER5L	ENSHCOP00000016312	ENSHCOP00000001417	DUF4585 domain-containing protein.	Immediate early response 5-like.	0.585
cunh10orf71	tm9sf4	ENSHCOP00000016312	ENSHCOP00000003242	DUF4585 domain-containing protein.	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.	0.521
get3	IER5L	ENSHCOP00000016046	ENSHCOP00000001417	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Immediate early response 5-like.	0.579
get3	naa25	ENSHCOP00000016046	ENSHCOP00000003522	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	N(alpha)-acetyltransferase 25, NatB auxiliary subunit.	0.583
get3	phax	ENSHCOP00000016046	ENSHCOP00000021966	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Phosphorylated adaptor for RNA export.	0.571
get3	psmc5	ENSHCOP00000016046	ENSHCOP00000014246	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.	0.430
naa25	Gen1	ENSHCOP00000003522	ENSHCOP00000024625	N(alpha)-acetyltransferase 25, NatB auxiliary subunit.	Uncharacterized protein.	0.405
naa25	IER5L	ENSHCOP00000003522	ENSHCOP00000001417	N(alpha)-acetyltransferase 25, NatB auxiliary subunit.	Immediate early response 5-like.	0.593
naa25	get3	ENSHCOP00000003522	ENSHCOP00000016046	N(alpha)-acetyltransferase 25, NatB auxiliary subunit.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.583
naa25	phax	ENSHCOP00000003522	ENSHCOP00000021966	N(alpha)-acetyltransferase 25, NatB auxiliary subunit.	Phosphorylated adaptor for RNA export.	0.585
phax	IER5L	ENSHCOP00000021966	ENSHCOP00000001417	Phosphorylated adaptor for RNA export.	Immediate early response 5-like.	0.586