STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnm1Dynamin 1a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (634 aa)    
Predicted Functional Partners:
gak
Cyclin G associated kinase.
   
 0.981
ENSHCOP00000018414
GED domain-containing protein.
 
     0.919
ENSHCOP00000009027
SH3 domain-containing protein.
    
 
 0.703
ENSHCOP00000009056
Uncharacterized protein.
    
 
 0.703
ENSHCOP00000023126
Uncharacterized protein.
    
 
 0.703
ENSHCOP00000027446
Uncharacterized protein.
    
 
 0.703
ENSHCOP00000027460
Uncharacterized protein.
    
 
 0.703
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6.
   
 0.700
itsn1
Intersectin 1 (SH3 domain protein).
    
 
 0.648
LOC109524747
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
   
 0.588
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.