STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gdf3Growth differentiation factor 3. (407 aa)    
Predicted Functional Partners:
LOC109522424
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.944
acvr2b
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.944
ACVR1B
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
    
 0.944
acvr2a
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.944
ACVR1C
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
    
 0.941
ENSHCOP00000018022
EGF-like domain-containing protein.
    
 0.655
nodal
Nodal-related 2.
   
 
0.608
LOC109510730
Southpaw.
   
 
0.608
ENSHCOP00000019560
TGF_BETA_2 domain-containing protein.
   
 
0.608
LOC109527971
POU domain protein.
   
 
 0.452
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.