STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSHCOP00000002481BCL2 apoptosis regulator b. (221 aa)    
Predicted Functional Partners:
bax
BCL2 associated X, apoptosis regulator a.
    
 
 0.935
becn1
Beclin 1, autophagy related.
    
 
 0.927
bad
Uncharacterized protein.
   
 0.874
LOC109528457
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 0.830
bcl2l1
BCL2 like 1.
    
0.806
Apaf1
Apoptotic peptidase activating factor 1.
    
 
 0.793
LOC109508060
Zgc:153993.
    
 
0.771
ENSHCOP00000006047
Uncharacterized protein.
    
 0.689
bmf
Bcl2 modifying factor.
    
 0.689
LOC109522925
FKBP prolyl isomerase 16.
    
 
 0.654
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.