STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSHCOP00000003686PDZ domain-containing protein. (181 aa)    
Predicted Functional Partners:
grip1
Glutamate receptor interacting protein 1.
 
     
0.900
pick1
Protein interacting with prkca 1.
    
 0.773
LOC109515646
Uncharacterized protein.
    
 0.589
LOC109524392
Glutamate receptor, ionotropic, AMPA 1a.
    
 0.589
LOC109515834
Glutamate ionotropic receptor AMPA type subunit 3.
    
 0.589
gria3
Glutamate receptor, ionotropic, AMPA 3a.
    
 0.589
GRIA2
Glutamate ionotropic receptor AMPA type subunit 2.
    
 0.589
LOC109516917
Uncharacterized protein.
    
 0.589
ENSHCOP00000025225
PBPe domain-containing protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
    
 0.589
ap2m1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
   
 
 0.515
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.