STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plcd4Phosphoinositide phospholipase C. (746 aa)    
Predicted Functional Partners:
INPP5A
Inositol polyphosphate-5-phosphatase A.
   
 
 0.912
ipmk
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.910
cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
     
 0.908
Itpr1
MIR domain-containing protein.
   
 
 0.906
LOC109510405
Inositol polyphosphate-5-phosphatase Jb.
     
 0.905
inpp5e
Inositol polyphosphate-5-phosphatase E.
     
 0.903
LOC109528785
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.902
PTEN
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.902
ocrl
OCRL inositol polyphosphate-5-phosphatase.
     
 0.901
mtm1
Myotubularin 1.
     
 0.901
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.