Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LOC109528457 | LOC109531265 | ENSHCOP00000022970 | ENSHCOP00000006973 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | BRCA1 associated RING domain 1. | 0.880 |
| LOC109528457 | chek1 | ENSHCOP00000022970 | ENSHCOP00000027175 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Checkpoint kinase 1; Belongs to the protein kinase superfamily. | 0.992 |
| LOC109528457 | chek2 | ENSHCOP00000022970 | ENSHCOP00000017184 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Checkpoint kinase 2. | 0.995 |
| LOC109528457 | mdm2 | ENSHCOP00000022970 | ENSHCOP00000019043 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | MDM2 proto-oncogene. | 0.999 |
| LOC109528457 | mdm4 | ENSHCOP00000022970 | ENSHCOP00000007016 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. | 0.999 |
| LOC109528457 | pwwp2a | ENSHCOP00000022970 | ENSHCOP00000006740 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | PWWP domain containing 2A. | 0.698 |
| LOC109528457 | rps27a | ENSHCOP00000022970 | ENSHCOP00000016034 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Ribosomal protein S27a. | 0.937 |
| LOC109528457 | tp53bp1 | ENSHCOP00000022970 | ENSHCOP00000020451 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Tumor protein p53 binding protein, 1. | 0.975 |
| LOC109528457 | tp63 | ENSHCOP00000022970 | ENSHCOP00000011142 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.755 |
| LOC109528457 | yap1 | ENSHCOP00000022970 | ENSHCOP00000022982 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Yes-associated protein 1. | 0.503 |
| LOC109531265 | LOC109528457 | ENSHCOP00000006973 | ENSHCOP00000022970 | BRCA1 associated RING domain 1. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.880 |
| LOC109531265 | chek1 | ENSHCOP00000006973 | ENSHCOP00000027175 | BRCA1 associated RING domain 1. | Checkpoint kinase 1; Belongs to the protein kinase superfamily. | 0.780 |
| LOC109531265 | chek2 | ENSHCOP00000006973 | ENSHCOP00000017184 | BRCA1 associated RING domain 1. | Checkpoint kinase 2. | 0.910 |
| LOC109531265 | mdm2 | ENSHCOP00000006973 | ENSHCOP00000019043 | BRCA1 associated RING domain 1. | MDM2 proto-oncogene. | 0.524 |
| LOC109531265 | pwwp2a | ENSHCOP00000006973 | ENSHCOP00000006740 | BRCA1 associated RING domain 1. | PWWP domain containing 2A. | 0.852 |
| LOC109531265 | rps27a | ENSHCOP00000006973 | ENSHCOP00000016034 | BRCA1 associated RING domain 1. | Ribosomal protein S27a. | 0.946 |
| LOC109531265 | tp53bp1 | ENSHCOP00000006973 | ENSHCOP00000020451 | BRCA1 associated RING domain 1. | Tumor protein p53 binding protein, 1. | 0.866 |
| LOC109531265 | tp63 | ENSHCOP00000006973 | ENSHCOP00000011142 | BRCA1 associated RING domain 1. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.755 |
| chek1 | LOC109528457 | ENSHCOP00000027175 | ENSHCOP00000022970 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.992 |
| chek1 | LOC109531265 | ENSHCOP00000027175 | ENSHCOP00000006973 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. | BRCA1 associated RING domain 1. | 0.780 |
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