STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (531 aa)    
Predicted Functional Partners:
wnt11
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
   
 0.985
lrp6
Low density lipoprotein receptor-related protein 6.
    
 0.983
ndp
Norrin cystine knot growth factor NDP.
    
 
 0.960
LOC109528682
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.931
LOC109520091
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.931
LOC109521193
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.914
bambi
BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a.
    
 0.913
LOC109524407
Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
     
 0.906
wnt4
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
    
 0.902
dvl2
Dishevelled segment polarity protein 2.
   
 0.898
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.