STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSHCOP00000012565GDNF domain-containing protein. (318 aa)    
Predicted Functional Partners:
ret
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.783
gdnf
Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.
    
 0.771
LOC109524125
TGF_BETA_2 domain-containing protein.
   
 
 0.724
nrtn
Neurturin.
    
 0.696
fam83b
Family with sequence similarity 83 member B.
      
 0.616
Artn
Artemin a.
    
 0.581
LOC109523032
G protein-coupled receptor 182; Belongs to the G-protein coupled receptor 1 family.
      
 0.569
cd79a
CD79a molecule, immunoglobulin-associated alpha.
      
 0.471
fgfr3
Fibroblast growth factor receptor.
    
 0.405
fgfr2
Fibroblast growth factor receptor.
    
 0.405
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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