STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metMET proto-oncogene, receptor tyrosine kinase. (1423 aa)    
Predicted Functional Partners:
hgf
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.968
LOC109517915
Uncharacterized protein.
   
 0.959
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
   
 0.959
LOC109531675
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
   
 0.959
grb2
Growth factor receptor-bound protein 2b.
    
 0.950
LOC109509855
Leucine-rich repeats and immunoglobulin-like domains 1.
    
 0.947
lrig2
Leucine-rich repeats and immunoglobulin-like domains 2.
    
 0.946
LRIG3
Leucine rich repeats and immunoglobulin like domains 3.
    
 0.946
ENSHCOP00000001893
Uncharacterized protein.
   
 0.945
ENSHCOP00000008210
Uncharacterized protein.
   
 0.945
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.