STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSHCOP00000013041B30.2/SPRY domain-containing protein. (200 aa)    
Predicted Functional Partners:
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.874
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.844
cul1
Cullin 1b; Belongs to the cullin family.
    
 0.774
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.712
LOC109506870
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.712
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
    
 0.683
mrpl2
Mitochondrial ribosomal protein L2.
    
 0.650
nedd8
NEDD8 ubiquitin like modifier, like.
    
 0.619
ubb
Ubiquitin B.
   
 0.605
ubc
Uncharacterized protein.
   
 0.605
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.