GNG5 protein (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GNG5

Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)

Predicted Functional Partners:

gnb5

0.880

LOC109513847

0.880

ADCY9

0.805

adcy3

0.803

LOC109524669

0.803

LOC109521217

0.803

LOC109513761

0.802

Pik3cg

0.802

PIK3R5

0.793

LOC109528420

0.785

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY9	GNG5	ENSHCOP00000006794	ENSHCOP00000014223	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.805
ADCY9	LOC109513847	ENSHCOP00000006794	ENSHCOP00000027991	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanine nucleotide binding protein (G protein), beta 5b.	0.812
ADCY9	LOC109521217	ENSHCOP00000006794	ENSHCOP00000016745	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.539
ADCY9	LOC109524669	ENSHCOP00000006794	ENSHCOP00000006394	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.539
ADCY9	LOC109528420	ENSHCOP00000006794	ENSHCOP00000005143	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.537
ADCY9	adcy3	ENSHCOP00000006794	ENSHCOP00000000049	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.537
ADCY9	gnb5	ENSHCOP00000006794	ENSHCOP00000015428	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanine nucleotide binding protein (G protein), beta 5a.	0.812
GNG5	ADCY9	ENSHCOP00000014223	ENSHCOP00000006794	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.805
GNG5	LOC109513761	ENSHCOP00000014223	ENSHCOP00000021209	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.802
GNG5	LOC109513847	ENSHCOP00000014223	ENSHCOP00000027991	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), beta 5b.	0.880
GNG5	LOC109521217	ENSHCOP00000014223	ENSHCOP00000016745	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.803
GNG5	LOC109524669	ENSHCOP00000014223	ENSHCOP00000006394	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.803
GNG5	LOC109528420	ENSHCOP00000014223	ENSHCOP00000005143	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.785
GNG5	PIK3R5	ENSHCOP00000014223	ENSHCOP00000021848	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Phosphoinositide-3-kinase regulatory subunit 5.	0.793
GNG5	Pik3cg	ENSHCOP00000014223	ENSHCOP00000022782	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	0.802
GNG5	adcy3	ENSHCOP00000014223	ENSHCOP00000000049	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.803
GNG5	gnb5	ENSHCOP00000014223	ENSHCOP00000015428	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide binding protein (G protein), beta 5a.	0.880
LOC109513761	GNG5	ENSHCOP00000021209	ENSHCOP00000014223	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.802
LOC109513761	LOC109513847	ENSHCOP00000021209	ENSHCOP00000027991	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Guanine nucleotide binding protein (G protein), beta 5b.	0.803
LOC109513761	PIK3R5	ENSHCOP00000021209	ENSHCOP00000021848	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphoinositide-3-kinase regulatory subunit 5.	0.960

page 1 of 4

Server load: low (28%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About