STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccnb1Cyclin B1; Belongs to the cyclin family. (396 aa)    
Predicted Functional Partners:
cdc20
Cell division cycle 20 homolog.
   
 0.996
cdk1
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.995
cdc27
Cell division cycle 27.
   
 0.985
anapc10
Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
   
 0.983
PLK1
Serine/threonine-protein kinase PLK.
   
 0.980
cdc23
CDC23 (cell division cycle 23, yeast, homolog).
   
 0.970
cdc16
Cell division cycle 16 homolog (S. cerevisiae).
   
 0.960
anapc2
Anaphase promoting complex subunit 2; Belongs to the cullin family.
   
 0.956
anapc11
APC11 anaphase promoting complex subunit 11 homolog (yeast).
   
 0.955
anapc7
Anaphase promoting complex subunit 7.
   
 
 0.951
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.