STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
irf5Interferon regulatory factor 5. (452 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.611
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.529
stat1
Signal transducer and activator of transcription.
   
 0.492
ripk4
Receptor-interacting serine-threonine kinase 4.
   
 0.477
LOC109515677
Interferon regulatory factor.
  
0.475
plk3
Serine/threonine-protein kinase PLK.
   
 0.456
PLK1
Serine/threonine-protein kinase PLK.
   
 0.456
plk2
Serine/threonine-protein kinase PLK.
   
 0.456
il10
Uncharacterized protein.
   
 
 0.452
cdc25b
Rhodanese domain-containing protein.
   
 0.433
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.