STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (879 aa)    
Predicted Functional Partners:
grip1
Glutamate receptor interacting protein 1.
    
 0.982
pick1
Protein interacting with prkca 1.
    
 0.975
LOC109527809
Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
 0.931
LOC109509103
Cornichon family AMPA receptor auxiliary protein 2.
    
 0.915
LOC109531791
Cornichon family AMPA receptor auxiliary protein 3.
    
 0.915
LOC109516917
Uncharacterized protein.
  
0.822
LOC109524392
Glutamate receptor, ionotropic, AMPA 1a.
  
0.821
LOC109515834
Glutamate ionotropic receptor AMPA type subunit 3.
  
0.819
LOC109515646
Uncharacterized protein.
  
0.818
gria3
Glutamate receptor, ionotropic, AMPA 3a.
  
0.818
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.