node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC109512012 | fdps | ENSHCOP00000025625 | ENSHCOP00000020866 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. | 0.706 |
LOC109512012 | hmgcs1 | ENSHCOP00000025625 | ENSHCOP00000011483 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.974 |
LOC109512012 | idi1 | ENSHCOP00000025625 | ENSHCOP00000023430 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | Isopentenyl-diphosphate delta isomerase 1. | 0.946 |
LOC109512012 | lss | ENSHCOP00000025625 | ENSHCOP00000020573 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.999 |
LOC109512012 | mvd | ENSHCOP00000025625 | ENSHCOP00000003701 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.837 |
LOC109512012 | sqle | ENSHCOP00000025625 | ENSHCOP00000011311 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | Squalene epoxidase a. | 0.989 |
coq2 | dhdds | ENSHCOP00000006208 | ENSHCOP00000004286 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Alkyl transferase; Belongs to the UPP synthase family. | 0.933 |
coq2 | fdps | ENSHCOP00000006208 | ENSHCOP00000020866 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. | 0.662 |
coq2 | ggps1 | ENSHCOP00000006208 | ENSHCOP00000022439 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | 0.803 |
coq2 | hmgcs1 | ENSHCOP00000006208 | ENSHCOP00000011483 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.471 |
coq2 | idi1 | ENSHCOP00000006208 | ENSHCOP00000023430 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Isopentenyl-diphosphate delta isomerase 1. | 0.967 |
coq2 | lss | ENSHCOP00000006208 | ENSHCOP00000020573 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.831 |
coq2 | mvd | ENSHCOP00000006208 | ENSHCOP00000003701 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.516 |
coq2 | nus1 | ENSHCOP00000006208 | ENSHCOP00000010165 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | NUS1 dehydrodolichyl diphosphate synthase subunit. | 0.933 |
coq2 | sqle | ENSHCOP00000006208 | ENSHCOP00000011311 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Squalene epoxidase a. | 0.856 |
dhdds | coq2 | ENSHCOP00000004286 | ENSHCOP00000006208 | Alkyl transferase; Belongs to the UPP synthase family. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.933 |
dhdds | fdps | ENSHCOP00000004286 | ENSHCOP00000020866 | Alkyl transferase; Belongs to the UPP synthase family. | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. | 0.959 |
dhdds | ggps1 | ENSHCOP00000004286 | ENSHCOP00000022439 | Alkyl transferase; Belongs to the UPP synthase family. | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | 0.965 |
dhdds | hmgcs1 | ENSHCOP00000004286 | ENSHCOP00000011483 | Alkyl transferase; Belongs to the UPP synthase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.570 |
dhdds | idi1 | ENSHCOP00000004286 | ENSHCOP00000023430 | Alkyl transferase; Belongs to the UPP synthase family. | Isopentenyl-diphosphate delta isomerase 1. | 0.941 |