STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbx5Uncharacterized protein. (476 aa)    
Predicted Functional Partners:
nkx2-5
NK2 homeobox 5.
   
 
 0.868
yap1
Yes-associated protein 1.
    
 0.727
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.467
hand2
Heart and neural crest derivatives expressed 2.
   
 0.465
LOC109528291
Uncharacterized protein.
     
 0.407
ENSHCOP00000006266
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
      
 0.405
LOC109531218
Transducin beta like 1 X-linked.
    
 
 0.402
LOC109520496
Transducin (beta)-like 1 X-linked receptor 1b.
    
 
 0.402
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.