STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0D3D9Z6Origin of replication complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (417 aa)    
Predicted Functional Partners:
A0A0D3BR67
Uncharacterized protein.
   
 0.993
A0A0D3EEZ4
ORC_WH_C domain-containing protein.
   
 0.992
A0A0D3DR85
Uncharacterized protein.
   
 0.991
A0A0D3CU94
AAA_16 domain-containing protein.
   
 0.990
A0A0D3DTU6
Uncharacterized protein.
   
 0.990
A0A0D3E8D0
Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
   
0.989
A0A0D3BDZ0
DNA helicase; Belongs to the MCM family.
   
 0.985
A0A0D3AA15
Uncharacterized protein.
   
 0.982
A0A0D3AUJ0
DNA helicase; Belongs to the MCM family.
   
 0.978
A0A0D3B8W3
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 0.978
Your Current Organism:
Brassica oleracea
NCBI taxonomy Id: 109376
Other names: B. oleracea var. oleracea, Brassica oleracea subsp. oleracea, Brassica oleracea var. oleracea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.