E0L32_010490 protein (Phialemoniopsis curvata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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filled nodes:
a 3D structure is known or predicted

Edges:

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

E0L32_010490

Uncharacterized protein. (809 aa)

Predicted Functional Partners:

E0L32_008732

0.972

E0L32_004383

0.966

E0L32_003075

0.955

E0L32_012340

0.955

E0L32_003568

0.952

E0L32_007205

0.951

E0L32_001733

0.949

E0L32_006541

0.947

E0L32_005524

0.947

E0L32_002944

0.945

Your Current Organism:

Phialemoniopsis curvata

NCBI taxonomy Id: 1093900
Other names: Bionectriaceae sp. NRRL 46124, CBS 490.82, CDC 45-394-63, P. curvata, Phialemoniopsis curvata (W. Gams & W. B. Cooke) H. Perdomo, D. Garca, Gen, Cano & Guarro 2013, Phialemonium curvatum, Xylariales sp. HP-2011b

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E0L32_001733	E0L32_002944	A0A507ATY8	A0A507BEC7	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.997
E0L32_001733	E0L32_003075	A0A507ATY8	A0A507B5A1	TPR_REGION domain-containing protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.854
E0L32_001733	E0L32_003568	A0A507ATY8	A0A507B9V5	TPR_REGION domain-containing protein.	Protein kinase domain-containing protein.	0.919
E0L32_001733	E0L32_004383	A0A507ATY8	A0A507B6U3	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.988
E0L32_001733	E0L32_005524	A0A507ATY8	A0A507BBV5	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.997
E0L32_001733	E0L32_006541	A0A507ATY8	A0A507AQH8	TPR_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.939
E0L32_001733	E0L32_007205	A0A507ATY8	A0A507B632	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.997
E0L32_001733	E0L32_008732	A0A507ATY8	A0A507AS81	TPR_REGION domain-containing protein.	HORMA domain-containing protein.	0.989
E0L32_001733	E0L32_010490	A0A507ATY8	A0A507AK81	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.949
E0L32_001733	E0L32_012340	A0A507ATY8	A0A507BCN1	TPR_REGION domain-containing protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.818
E0L32_002944	E0L32_001733	A0A507BEC7	A0A507ATY8	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.997
E0L32_002944	E0L32_003075	A0A507BEC7	A0A507B5A1	Uncharacterized protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.805
E0L32_002944	E0L32_003568	A0A507BEC7	A0A507B9V5	Uncharacterized protein.	Protein kinase domain-containing protein.	0.905
E0L32_002944	E0L32_004383	A0A507BEC7	A0A507B6U3	Uncharacterized protein.	Uncharacterized protein.	0.985
E0L32_002944	E0L32_005524	A0A507BEC7	A0A507BBV5	Uncharacterized protein.	Uncharacterized protein.	0.998
E0L32_002944	E0L32_006541	A0A507BEC7	A0A507AQH8	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.900
E0L32_002944	E0L32_007205	A0A507BEC7	A0A507B632	Uncharacterized protein.	Uncharacterized protein.	0.997
E0L32_002944	E0L32_008732	A0A507BEC7	A0A507AS81	Uncharacterized protein.	HORMA domain-containing protein.	0.985
E0L32_002944	E0L32_010490	A0A507BEC7	A0A507AK81	Uncharacterized protein.	Uncharacterized protein.	0.945
E0L32_002944	E0L32_012340	A0A507BEC7	A0A507BCN1	Uncharacterized protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.754

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

25

average node degree:

4.55

avg. local clustering coefficient:

0.939

expected number of edges:

35

PPI enrichment p-value:

0.966

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009306

Protein secretion

4 of 41

1.5

1.05

0.0048

GO:0015031

Protein transport

5 of 87

1.27

0.92

0.0048

GO:0007165

Signal transduction

6 of 351

0.75

0.47

0.0219

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005886

Plasma membrane

10 of 615

0.73

0.67

3.15e-05

GO:0016021

Integral component of membrane

10 of 844

0.59

0.5

0.00023

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3083

Mixed, incl. PAC motif, and Putative sensory transducer protein YvaQ-like, ligand-binding sensor domain

5 of 14

2.07

2.91

7.68e-07

CL:3085

Mixed, incl. Double Cache domain 1, and Putative sensory transducer protein YvaQ-like, ligand-binding sensor domain

3 of 6

2.21

5.02e-05

CL:3064

His Kinase A (phosphoacceptor) domain, and EAL domain

6 of 51

1.58

2.18

1.39e-06

CL:4797

Bacterial secretion system, and Pilus organization

5 of 53

1.49

1.77

1.59e-05

CL:4800

Type II/IV secretion system protein, and Export from cell

4 of 32

1.61

1.74

6.94e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03070

Bacterial secretion system

5 of 75

1.34

1.32

0.00022

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0016020

Membrane

10 of 707

0.66

0.57

0.00022

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0418

Kinase

4 of 149

0.94

0.5

0.0432

KW-1133

Transmembrane helix

8 of 689

0.58

0.36

0.0377

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00482

Type II secretion system (T2SS), protein F

4 of 4

2.51

3.03

1.85e-06

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR042094

Type II secretion system GspF domain superfamily

4 of 4

2.51

2.82

4.77e-06

IPR018076

Type II secretion system protein GspF domain

4 of 4

2.51

2.82

4.77e-06

IPR003004

GspF/PilC family

4 of 4

2.51

2.82

4.77e-06

IPR003661

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain

6 of 109

1.26

0.00014

IPR036097

Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily

6 of 116

1.23

1.22

0.00016

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00388

His Kinase A (phosphoacceptor) domain

6 of 115

1.23

1.31

5.64e-05

SM00387

Histidine kinase-like ATPases

6 of 131

1.18

1.23

5.92e-05

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