E0L32_010068 protein (Phialemoniopsis curvata)

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

E0L32_010068

J domain-containing protein. (949 aa)

Predicted Functional Partners:

E0L32_001540

0.662

E0L32_005727

0.661

E0L32_001454

0.612

E0L32_004058

0.612

E0L32_001814

0.551

E0L32_010954

0.464

E0L32_010866

0.464

E0L32_006993

0.464

E0L32_006134

0.464

E0L32_006221

0.464

Your Current Organism:

Phialemoniopsis curvata

NCBI taxonomy Id: 1093900
Other names: Bionectriaceae sp. NRRL 46124, CBS 490.82, CDC 45-394-63, P. curvata, Phialemoniopsis curvata (W. Gams & W. B. Cooke) H. Perdomo, D. Garca, Gen, Cano & Guarro 2013, Phialemonium curvatum, Xylariales sp. HP-2011b

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E0L32_001454	E0L32_001540	A0A507AS13	A0A507AWJ3	Uncharacterized protein.	NMD3 domain-containing protein.	0.961
E0L32_001454	E0L32_005727	A0A507AS13	A0A507B1M6	Uncharacterized protein.	Peptidase_M24 domain-containing protein.	0.934
E0L32_001454	E0L32_010068	A0A507AS13	A0A507AU72	Uncharacterized protein.	J domain-containing protein.	0.612
E0L32_001540	E0L32_001454	A0A507AWJ3	A0A507AS13	NMD3 domain-containing protein.	Uncharacterized protein.	0.961
E0L32_001540	E0L32_004058	A0A507AWJ3	A0A507BGG0	NMD3 domain-containing protein.	zf-C2H2_2 domain-containing protein.	0.961
E0L32_001540	E0L32_005727	A0A507AWJ3	A0A507B1M6	NMD3 domain-containing protein.	Peptidase_M24 domain-containing protein.	0.995
E0L32_001540	E0L32_010068	A0A507AWJ3	A0A507AU72	NMD3 domain-containing protein.	J domain-containing protein.	0.662
E0L32_001814	E0L32_010068	A0A507AVM2	A0A507AU72	UBA domain-containing protein.	J domain-containing protein.	0.551
E0L32_004058	E0L32_001540	A0A507BGG0	A0A507AWJ3	zf-C2H2_2 domain-containing protein.	NMD3 domain-containing protein.	0.961
E0L32_004058	E0L32_005727	A0A507BGG0	A0A507B1M6	zf-C2H2_2 domain-containing protein.	Peptidase_M24 domain-containing protein.	0.934
E0L32_004058	E0L32_010068	A0A507BGG0	A0A507AU72	zf-C2H2_2 domain-containing protein.	J domain-containing protein.	0.612
E0L32_005727	E0L32_001454	A0A507B1M6	A0A507AS13	Peptidase_M24 domain-containing protein.	Uncharacterized protein.	0.934
E0L32_005727	E0L32_001540	A0A507B1M6	A0A507AWJ3	Peptidase_M24 domain-containing protein.	NMD3 domain-containing protein.	0.995
E0L32_005727	E0L32_004058	A0A507B1M6	A0A507BGG0	Peptidase_M24 domain-containing protein.	zf-C2H2_2 domain-containing protein.	0.934
E0L32_005727	E0L32_010068	A0A507B1M6	A0A507AU72	Peptidase_M24 domain-containing protein.	J domain-containing protein.	0.661
E0L32_006134	E0L32_010068	A0A507B3V2	A0A507AU72	Uncharacterized protein.	J domain-containing protein.	0.464
E0L32_006221	E0L32_010068	A0A507B8V2	A0A507AU72	F-box domain-containing protein.	J domain-containing protein.	0.464
E0L32_006993	E0L32_010068	A0A507AZU7	A0A507AU72	F-box domain-containing protein.	J domain-containing protein.	0.464
E0L32_010068	E0L32_001454	A0A507AU72	A0A507AS13	J domain-containing protein.	Uncharacterized protein.	0.612
E0L32_010068	E0L32_001540	A0A507AU72	A0A507AWJ3	J domain-containing protein.	NMD3 domain-containing protein.	0.662

page 1 of 2

Network Stats

number of nodes:

7

number of edges:

16

average node degree:

4.57

avg. local clustering coefficient:

0.952

expected number of edges:

6

PPI enrichment p-value:

0.000749

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005976

Polysaccharide metabolic process

7 of 36

1.9

3.66

9.33e-10

GO:0009250

Glucan biosynthetic process

4 of 5

2.51

3.15

1.05e-06

GO:0005975

Carbohydrate metabolic process

10 of 161

1.4

2.44

7.05e-11

GO:0005978

Glycogen biosynthetic process

3 of 4

2.48

2.28

5.42e-05

GO:0009059

Macromolecule biosynthetic process

5 of 278

0.86

0.53

0.0209

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004339

Glucan 1,4-alpha-glucosidase activity

3 of 3

2.61

2.3

5.39e-05

GO:0016757

Glycosyltransferase activity

6 of 77

1.5

1.83

1.08e-05

GO:0004553

Hydrolase activity, hydrolyzing O-glycosyl compounds

4 of 30

1.73

1.75

0.00013

GO:0030246

Carbohydrate binding

3 of 11

2.04

1.68

0.00049

GO:0016758

Hexosyltransferase activity

3 of 17

1.85

1.47

0.0010

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031470

Carboxysome

2 of 3

2.43

1.17

0.0072

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2654

Glucan metabolic process, and Glucosidase activity

9 of 13

2.45

7.86

1.36e-17

CL:2576

Mixed, incl. Polysaccharide metabolic process, and Glycosyl hydrolase, all-beta

11 of 65

1.84

5.21

1.36e-17

CL:2658

Glycogen metabolic process

4 of 5

2.51

3.39

3.44e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00500

Starch and sucrose metabolism

8 of 39

1.92

4.49

1.65e-12

map00520

Amino sugar and nucleotide sugar metabolism

4 of 54

1.48

1.35

0.00050

map00051

Fructose and mannose metabolism

2 of 20

1.61

0.75

0.0313

map01110

Biosynthesis of secondary metabolites

7 of 503

0.75

0.58

0.0022

map01100

Metabolic pathways

10 of 1398

0.46

0.37

0.0024

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0010170

glucose-1-phosphate adenylyltransferase complex

2 of 2

2.61

1.08

0.0107

GOCC:1990234

Transferase complex

4 of 104

1.19

0.78

0.0107

GOCC:0032991

Protein-containing complex

6 of 477

0.71

0.42

0.0361

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0119

Carbohydrate metabolism

3 of 14

1.94

1.41

0.0016

KW-0321

Glycogen metabolism

2 of 2

2.61

1.34

0.0036

KW-0320

Glycogen biosynthesis

2 of 3

2.43

1.3

0.0040

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00723

Glycosyl hydrolases family 15

3 of 3

2.61

2.09

0.00014

PF12804

MobA-like NTP transferase domain

3 of 10

2.08

1.55

0.0010

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR005835

Nucleotidyl transferase domain

4 of 8

2.31

2.48

1.63e-05

IPR011613

GH15-like domain

3 of 3

2.61

2.02

0.00019

IPR012341

Six-hairpin glycosidase-like superfamily

3 of 6

2.31

1.8

0.00039

IPR008928

Six-hairpin glycosidase superfamily

3 of 6

2.31

1.8

0.00039

IPR029044

Nucleotide-diphospho-sugar transferases

4 of 25

1.81

1.69

0.00026

(more ...)

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