E0L32_005757 protein (Phialemoniopsis curvata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

E0L32_005757

HET domain-containing protein. (721 aa)

Predicted Functional Partners:

E0L32_003227

0.933

E0L32_005534

0.931

E0L32_009720

0.927

E0L32_000651

0.927

E0L32_011666

0.925

E0L32_007383

0.915

E0L32_008838

0.915

E0L32_008188

0.914

E0L32_004717

0.909

E0L32_008491

0.905

Your Current Organism:

Phialemoniopsis curvata

NCBI taxonomy Id: 1093900
Other names: Bionectriaceae sp. NRRL 46124, CBS 490.82, CDC 45-394-63, P. curvata, Phialemoniopsis curvata (W. Gams & W. B. Cooke) H. Perdomo, D. Garca, Gen, Cano & Guarro 2013, Phialemonium curvatum, Xylariales sp. HP-2011b

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E0L32_000651	E0L32_003227	A0A507B3C9	A0A507BI93	Uncharacterized protein.	Ribosomal_S10 domain-containing protein.	0.999
E0L32_000651	E0L32_004717	A0A507B3C9	A0A507BCM9	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	0.999
E0L32_000651	E0L32_005534	A0A507B3C9	A0A507BBW4	Uncharacterized protein.	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family.	0.999
E0L32_000651	E0L32_005757	A0A507B3C9	A0A507B1Q7	Uncharacterized protein.	HET domain-containing protein.	0.927
E0L32_000651	E0L32_007383	A0A507B3C9	A0A507AMG8	Uncharacterized protein.	Uncharacterized protein.	0.998
E0L32_000651	E0L32_008188	A0A507B3C9	A0A507B0J4	Uncharacterized protein.	Ribosomal_L23eN domain-containing protein.	0.999
E0L32_000651	E0L32_008491	A0A507B3C9	A0A507AJS1	Uncharacterized protein.	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.	0.998
E0L32_000651	E0L32_008838	A0A507B3C9	A0A507AYQ5	Uncharacterized protein.	Uncharacterized protein.	0.999
E0L32_000651	E0L32_009720	A0A507B3C9	A0A507AWX6	Uncharacterized protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS19 family.	0.999
E0L32_000651	E0L32_011666	A0A507B3C9	A0A507B5M7	Uncharacterized protein.	Ribosomal_L18_c domain-containing protein.	0.999
E0L32_003227	E0L32_000651	A0A507BI93	A0A507B3C9	Ribosomal_S10 domain-containing protein.	Uncharacterized protein.	0.999
E0L32_003227	E0L32_004717	A0A507BI93	A0A507BCM9	Ribosomal_S10 domain-containing protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family.	0.999
E0L32_003227	E0L32_005534	A0A507BI93	A0A507BBW4	Ribosomal_S10 domain-containing protein.	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family.	0.999
E0L32_003227	E0L32_005757	A0A507BI93	A0A507B1Q7	Ribosomal_S10 domain-containing protein.	HET domain-containing protein.	0.933
E0L32_003227	E0L32_007383	A0A507BI93	A0A507AMG8	Ribosomal_S10 domain-containing protein.	Uncharacterized protein.	0.998
E0L32_003227	E0L32_008188	A0A507BI93	A0A507B0J4	Ribosomal_S10 domain-containing protein.	Ribosomal_L23eN domain-containing protein.	0.999
E0L32_003227	E0L32_008491	A0A507BI93	A0A507AJS1	Ribosomal_S10 domain-containing protein.	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.	0.999
E0L32_003227	E0L32_008838	A0A507BI93	A0A507AYQ5	Ribosomal_S10 domain-containing protein.	Uncharacterized protein.	0.999
E0L32_003227	E0L32_009720	A0A507BI93	A0A507AWX6	Ribosomal_S10 domain-containing protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uS19 family.	0.999
E0L32_003227	E0L32_011666	A0A507BI93	A0A507B5M7	Ribosomal_S10 domain-containing protein.	Ribosomal_L18_c domain-containing protein.	0.999

page 1 of 6

Network Stats

number of nodes:

8

number of edges:

11

average node degree:

2.75

avg. local clustering coefficient:

0.899

expected number of edges:

7

PPI enrichment p-value:

0.102

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0071786

Endoplasmic reticulum tubular network organization

4 of 4

3.32

5.04

5.54e-09

GO:1990809

Endoplasmic reticulum tubular network membrane organization

2 of 2

3.32

1.82

0.0011

GO:0006997

Nucleus organization

2 of 27

2.19

0.82

0.0429

GO:0006996

Organelle organization

5 of 1022

1.01

0.62

0.0254

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0071782

Endoplasmic reticulum tubular network

2 of 20

2.32

1.3

0.0065

GO:0005789

Endoplasmic reticulum membrane

4 of 346

1.38

1.04

0.0052

GO:0031090

Organelle membrane

6 of 1051

1.08

0.92

0.0013

GO:0005737

Cytoplasm

8 of 5447

0.49

0.34

0.0132

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:22939

Mixed, incl. Interferon gamma signaling, and Endoplasmic reticulum tubular network organization

5 of 24

2.64

5.08

1.42e-09

CL:22941

Mixed, incl. Endoplasmic reticulum tubular network organization, and GTP cyclohydrolase I

3 of 10

2.8

2.89

1.60e-05

CL:22943

Endoplasmic reticulum tubular network organization, and Dynamin family

2 of 5

2.92

1.59

0.0025

CL:22964

Mixed, incl. Interferon gamma signaling, and TB2/DP1, HVA22 family

2 of 7

2.78

1.51

0.0034

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0098827

Endoplasmic reticulum subcompartment

3 of 80

1.9

1.22

0.0066

GOCC:0071782

Endoplasmic reticulum tubular network

2 of 19

2.34

1.11

0.0143

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03134

TB2/DP1, HVA22 family

2 of 2

3.32

1.78

0.0013

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR004345

TB2/DP1/HVA22-related protein

2 of 2

3.32

1.5

0.0037

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