E0L32_011985 protein (Phialemoniopsis curvata)

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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Gene Fusion

Cooccurrence

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[Homology]

Score

E0L32_011985

Uncharacterized protein. (263 aa)

Predicted Functional Partners:

E0L32_003226

0.802

E0L32_010725

0.799

E0L32_007925

0.754

E0L32_000290

0.714

E0L32_003691

0.714

E0L32_004102

0.711

E0L32_000855

0.697

E0L32_002640

0.697

E0L32_008718

0.691

E0L32_008986

0.658

Your Current Organism:

Phialemoniopsis curvata

NCBI taxonomy Id: 1093900
Other names: Bionectriaceae sp. NRRL 46124, CBS 490.82, CDC 45-394-63, P. curvata, Phialemoniopsis curvata (W. Gams & W. B. Cooke) H. Perdomo, D. Garca, Gen, Cano & Guarro 2013, Phialemonium curvatum, Xylariales sp. HP-2011b

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E0L32_000290	E0L32_003226	A0A507B9U4	A0A507BK69	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	Uncharacterized protein.	0.840
E0L32_000290	E0L32_003691	A0A507B9U4	A0A507BJH2	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	6-phosphogluconate dehydrogenase, decarboxylating; Belongs to the 6-phosphogluconate dehydrogenase family.	0.769
E0L32_000290	E0L32_004102	A0A507B9U4	A0A507B8F2	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	Uncharacterized protein.	0.433
E0L32_000290	E0L32_007925	A0A507B9U4	A0A507AX84	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	Uncharacterized protein.	0.583
E0L32_000290	E0L32_008718	A0A507B9U4	A0A507AR81	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	Uncharacterized protein.	0.497
E0L32_000290	E0L32_010725	A0A507B9U4	A0A507AM68	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	Uncharacterized protein.	0.714
E0L32_000290	E0L32_011985	A0A507B9U4	A0A507B6K7	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	Uncharacterized protein.	0.714
E0L32_000855	E0L32_002640	A0A507B7E5	A0A507BLN5	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.750
E0L32_000855	E0L32_011985	A0A507B7E5	A0A507B6K7	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Uncharacterized protein.	0.697
E0L32_002640	E0L32_000855	A0A507BLN5	A0A507B7E5	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.750
E0L32_002640	E0L32_011985	A0A507BLN5	A0A507B6K7	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	Uncharacterized protein.	0.697
E0L32_003226	E0L32_000290	A0A507BK69	A0A507B9U4	Uncharacterized protein.	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.840
E0L32_003226	E0L32_003691	A0A507BK69	A0A507BJH2	Uncharacterized protein.	6-phosphogluconate dehydrogenase, decarboxylating; Belongs to the 6-phosphogluconate dehydrogenase family.	0.840
E0L32_003226	E0L32_004102	A0A507BK69	A0A507B8F2	Uncharacterized protein.	Uncharacterized protein.	0.633
E0L32_003226	E0L32_007925	A0A507BK69	A0A507AX84	Uncharacterized protein.	Uncharacterized protein.	0.751
E0L32_003226	E0L32_008718	A0A507BK69	A0A507AR81	Uncharacterized protein.	Uncharacterized protein.	0.685
E0L32_003226	E0L32_010725	A0A507BK69	A0A507AM68	Uncharacterized protein.	Uncharacterized protein.	0.802
E0L32_003226	E0L32_011985	A0A507BK69	A0A507B6K7	Uncharacterized protein.	Uncharacterized protein.	0.802
E0L32_003691	E0L32_000290	A0A507BJH2	A0A507B9U4	6-phosphogluconate dehydrogenase, decarboxylating; Belongs to the 6-phosphogluconate dehydrogenase family.	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.769
E0L32_003691	E0L32_003226	A0A507BJH2	A0A507BK69	6-phosphogluconate dehydrogenase, decarboxylating; Belongs to the 6-phosphogluconate dehydrogenase family.	Uncharacterized protein.	0.840

page 1 of 4

Network Stats

number of nodes:

8

number of edges:

28

average node degree:

7

avg. local clustering coefficient:

1

expected number of edges:

7

PPI enrichment p-value:

1.51e-09

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0044249

Cellular biosynthetic process

11 of 601

0.73

0.68

1.19e-05

GO:1901576

Organic substance biosynthetic process

11 of 628

0.71

0.66

1.19e-05

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016757

Glycosyltransferase activity

11 of 70

1.66

4.05

7.40e-16

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016020

Membrane

11 of 791

0.61

0.54

3.02e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3822

Mixed, incl. Glycosyl transferases group 1, and Glycosyl transferase family 2

6 of 39

1.65

2.4

5.52e-07

CL:3824

Mixed, incl. Glycosyl transferases group 1, and Polysaccharide biosynthesis protein

5 of 28

1.72

2.21

5.21e-06

CL:3826

Mixed, incl. Glycosyltransferase Family 4, and Polysaccharide biosynthesis protein

4 of 17

1.84

2.04

3.82e-05

CL:3719

Mixed, incl. Nucleotide-diphospho-sugar transferases, and O-Antigen nucleotide sugar biosynthesis

9 of 165

1.2

1.59

1.16e-07

CL:3720

Mixed, incl. O-Antigen nucleotide sugar biosynthesis, and Nucleotide-diphospho-sugar transferases

8 of 147

1.2

1.52

6.32e-07

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0808

Transferase

11 of 364

0.94

1.12

9.33e-09

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13692

Glycosyl transferases group 1

11 of 25

2.11

7.28

2.73e-20

PF13439

Glycosyltransferase Family 4

9 of 18

2.16

6.34

5.41e-16

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR028098

Glycosyltransferase subfamily 4-like, N-terminal domain

10 of 22

2.12

6.57

2.47e-17

IPR001296

Glycosyl transferase, family 1

8 of 14

2.22

5.77

1.04e-13

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