E0L32_000158 protein (Phialemoniopsis curvata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

E0L32_000158

Uncharacterized protein. (641 aa)

Predicted Functional Partners:

E0L32_007194

0.982

E0L32_001771

0.972

E0L32_008324

0.836

E0L32_009913

0.836

E0L32_008950

0.836

E0L32_000287

0.836

E0L32_004667

0.836

E0L32_006164

0.835

E0L32_004165

0.835

E0L32_000974

0.808

Your Current Organism:

Phialemoniopsis curvata

NCBI taxonomy Id: 1093900
Other names: Bionectriaceae sp. NRRL 46124, CBS 490.82, CDC 45-394-63, P. curvata, Phialemoniopsis curvata (W. Gams & W. B. Cooke) H. Perdomo, D. Garca, Gen, Cano & Guarro 2013, Phialemonium curvatum, Xylariales sp. HP-2011b

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E0L32_000158	E0L32_000287	A0A507BB20	A0A507B8D9	Uncharacterized protein.	Uncharacterized protein.	0.836
E0L32_000158	E0L32_000974	A0A507BB20	A0A507AWN4	Uncharacterized protein.	Uncharacterized protein.	0.808
E0L32_000158	E0L32_001771	A0A507BB20	A0A507ALA9	Uncharacterized protein.	Uncharacterized protein.	0.972
E0L32_000158	E0L32_004165	A0A507BB20	A0A507BHX4	Uncharacterized protein.	Uncharacterized protein.	0.835
E0L32_000158	E0L32_004667	A0A507BB20	A0A507BCH7	Uncharacterized protein.	Uncharacterized protein; Belongs to the calmodulin family.	0.836
E0L32_000158	E0L32_006164	A0A507BB20	A0A507B3Y2	Uncharacterized protein.	DJ-1_PfpI domain-containing protein.	0.835
E0L32_000158	E0L32_007194	A0A507BB20	A0A507B416	Uncharacterized protein.	Uncharacterized protein.	0.982
E0L32_000158	E0L32_008324	A0A507BB20	A0A507AK27	Uncharacterized protein.	Uncharacterized protein.	0.836
E0L32_000158	E0L32_008950	A0A507BB20	A0A507AYP3	Uncharacterized protein.	Uncharacterized protein; Belongs to the calmodulin family.	0.836
E0L32_000158	E0L32_009913	A0A507BB20	A0A507AQ08	Uncharacterized protein.	Uncharacterized protein.	0.836
E0L32_000287	E0L32_000158	A0A507B8D9	A0A507BB20	Uncharacterized protein.	Uncharacterized protein.	0.836
E0L32_000287	E0L32_000974	A0A507B8D9	A0A507AWN4	Uncharacterized protein.	Uncharacterized protein.	0.640
E0L32_000287	E0L32_001771	A0A507B8D9	A0A507ALA9	Uncharacterized protein.	Uncharacterized protein.	0.865
E0L32_000287	E0L32_004165	A0A507B8D9	A0A507BHX4	Uncharacterized protein.	Uncharacterized protein.	0.790
E0L32_000287	E0L32_004667	A0A507B8D9	A0A507BCH7	Uncharacterized protein.	Uncharacterized protein; Belongs to the calmodulin family.	0.902
E0L32_000287	E0L32_006164	A0A507B8D9	A0A507B3Y2	Uncharacterized protein.	DJ-1_PfpI domain-containing protein.	0.790
E0L32_000287	E0L32_007194	A0A507B8D9	A0A507B416	Uncharacterized protein.	Uncharacterized protein.	0.821
E0L32_000287	E0L32_008324	A0A507B8D9	A0A507AK27	Uncharacterized protein.	Uncharacterized protein.	0.895
E0L32_000974	E0L32_000158	A0A507AWN4	A0A507BB20	Uncharacterized protein.	Uncharacterized protein.	0.808
E0L32_000974	E0L32_000287	A0A507AWN4	A0A507B8D9	Uncharacterized protein.	Uncharacterized protein.	0.640

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

21

average node degree:

3.82

avg. local clustering coefficient:

0.853

expected number of edges:

11

PPI enrichment p-value:

0.00482

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006817

Phosphate ion transport

6 of 6

2.42

4.61

6.26e-10

GO:0035435

Phosphate ion transmembrane transport

3 of 3

2.42

2.09

0.00012

GO:0006811

Ion transport

7 of 118

1.19

1.35

1.16e-05

GO:0006810

Transport

10 of 367

0.85

0.87

3.69e-06

GO:0055085

Transmembrane transport

7 of 287

0.81

0.61

0.0032

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005315

Inorganic phosphate transmembrane transporter activity

3 of 3

2.42

1.76

0.00052

GO:0022804

Active transmembrane transporter activity

4 of 81

1.11

0.57

0.0417

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2716

Phosphate ion transport

5 of 5

2.42

3.91

2.15e-08

CL:2685

Mixed, incl. Phosphate ion transport, and Ubiquinone metabolic process

7 of 22

1.92

3.72

9.40e-10

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02010

ABC transporters

7 of 93

1.3

1.65

1.61e-06

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0592

Phosphate transport

4 of 4

2.42

3.01

1.66e-06

KW-0813

Transport

5 of 109

1.08

0.82

0.0035

KW-0067

ATP-binding

6 of 228

0.84

0.6

0.0060

KW-1003

Cell membrane

4 of 130

0.91

0.48

0.0475

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR003439

ABC transporter-like, ATP-binding domain

4 of 33

1.5

0.95

0.0086

IPR017911

MacB, ATP-binding domain

2 of 2

2.42

0.72

0.0483

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00382

ATPases associated with a variety of cellular activities

4 of 82

1.11

0.65

0.0210

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