STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tsac_0132Integrase family protein; PFAM: Integrase, catalytic core, phage; KEGG: txy:Thexy_2018 integrase family protein. (186 aa)    
Predicted Functional Partners:
Tsac_2194
Protein of unknown function DUF710; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
  
  
 0.591
Tsac_1949
PFAM: Late competence development protein ComFB; KEGG: txy:Thexy_1164 Late competence development protein ComFB.
  
     0.527
hslV
ATP-dependent protease hslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
  
  
 0.435
Tsac_1101
PFAM: TnsA endonuclease, N-terminal; TnsA endonuclease C-terminal; KEGG: cth:Cthe_1117 Tn7-like transposition protein A.
  
     0.431
Tsac_1102
PFAM: Integrase, catalytic core; KEGG: cth:Cthe_1116 HMG-I and HMG-Y, DNA-binding.
  
     0.420
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.416
Tsac_1103
KEGG: cth:Cthe_1115 Tn7-like transposition protein C.
  
     0.405
Tsac_1619
PFAM: Prephenate dehydrogenase; KEGG: txy:Thexy_1112 Prephenate dehydrogenase.
  
    0.402
Tsac_1104
KEGG: cth:Cthe_1114 Tn7-like transposition protein D.
  
     0.401
Tsac_2683
PFAM: Phosphoribosyltransferase; KEGG: txy:Thexy_1896 phosphoribosyltransferase.
   
    0.400
Your Current Organism:
Thermoanaerobacterium saccharolyticum
NCBI taxonomy Id: 1094508
Other names: T. saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum str. JW/SL-YS485, Thermoanaerobacterium saccharolyticum strain JW/SL-YS485, Thermoanaerobacterium sp. (strain JW/SL YS485)
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