STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tsac_0542PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: txy:Thexy_2405 Cobyrinic acid ac-diamide synthase. (267 aa)    
Predicted Functional Partners:
Tsac_0541
TIGRFAM: ParB-like partition protein; PFAM: ParB-like nuclease; KEGG: txy:Thexy_2404 ParB-like partition protein; SMART: ParB-like nuclease; Belongs to the ParB family.
 
 0.998
Tsac_0543
TIGRFAM: ParB-like partition protein; PFAM: ParB-like nuclease; KEGG: txy:Thexy_2406 ParB-like partition protein; SMART: ParB-like nuclease; Belongs to the ParB family.
 
 0.984
dnaA
Chromosomal replication initiator protein dnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 0.690
rsmG
Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
  
 0.629
Tsac_0538
KEGG: txy:Thexy_2401 hypothetical protein.
  
  
 0.605
Tsac_0549
KEGG: txy:Thexy_2412 membrane protein insertase, YidC/Oxa1 family; TIGRFAM: Membrane insertion protein, OxaA/YidC, core; PFAM: Membrane insertion protein, OxaA/YidC.
 
   
 0.566
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
    0.555
mnmE
tRNA modification GTPase mnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
  
    0.534
Tsac_0540
KEGG: txy:Thexy_2403 radical SAM protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB.
       0.531
Tsac_0539
KEGG: txy:Thexy_2402 cysteine desulfurase family protein; TIGRFAM: Cysteine desulfurase-related, unknown function; PFAM: Aminotransferase, class V/Cysteine desulfurase.
       0.526
Your Current Organism:
Thermoanaerobacterium saccharolyticum
NCBI taxonomy Id: 1094508
Other names: T. saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum str. JW/SL-YS485, Thermoanaerobacterium saccharolyticum strain JW/SL-YS485, Thermoanaerobacterium sp. (strain JW/SL YS485)
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