STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tsac_0544PFAM: NUDIX hydrolase domain; KEGG: txy:Thexy_2407 NUDIX hydrolase. (148 aa)    
Predicted Functional Partners:
mnmG
tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
  
    0.741
mnmE
tRNA modification GTPase mnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
       0.739
rsmG
Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
       0.732
Tsac_0614
UPF0133 protein ybaB; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
 
     0.557
Tsac_0543
TIGRFAM: ParB-like partition protein; PFAM: ParB-like nuclease; KEGG: txy:Thexy_2406 ParB-like partition protein; SMART: ParB-like nuclease; Belongs to the ParB family.
       0.517
Tsac_0548
KEGG: txy:Thexy_2411 single-stranded nucleic acid binding R3H domain-containing protein; PFAM: Single-stranded nucleic acid binding R3H; SMART: Single-stranded nucleic acid binding R3H.
       0.506
Tsac_0549
KEGG: txy:Thexy_2412 membrane protein insertase, YidC/Oxa1 family; TIGRFAM: Membrane insertion protein, OxaA/YidC, core; PFAM: Membrane insertion protein, OxaA/YidC.
       0.506
Tsac_0550
UPF0161 protein yidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
  
    0.501
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
       0.491
Tsac_0542
PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: txy:Thexy_2405 Cobyrinic acid ac-diamide synthase.
  
    0.417
Your Current Organism:
Thermoanaerobacterium saccharolyticum
NCBI taxonomy Id: 1094508
Other names: T. saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum str. JW/SL-YS485, Thermoanaerobacterium saccharolyticum strain JW/SL-YS485, Thermoanaerobacterium sp. (strain JW/SL YS485)
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