STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tsac_0679NADH-ubiquinone oxidoreductase chain 49kDa; PFAM: NADH-quinone oxidoreductase, subunit D; Nickel-dependent hydrogenase, large subunit; KEGG: txy:Thexy_0110 NADH dehydrogenase (quinone). (360 aa)    
Predicted Functional Partners:
Tsac_0677
PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; KEGG: txy:Thexy_0108 NADH dehydrogenase (quinone).
 
 0.999
Tsac_0676
PFAM: NADH:ubiquinone oxidoreductase, subunit 1; KEGG: txy:Thexy_0107 respiratory-chain NADH dehydrogenase subunit 1.
 
 
 0.993
Tsac_0680
PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: txy:Thexy_0111 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
 
 
 0.981
Tsac_0675
NADH/Ubiquinone/plastoquinone (complex I); PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; NADH:ubiquinone oxidoreductase, chain 5/L, N-terminal; KEGG: txy:Thexy_0106 NADH dehydrogenase (quinone).
 
   
 0.971
Tsac_0678
KEGG: txy:Thexy_0109 NADH dehydrogenase (ubiquinone) 30 kDa subunit.
 
 
 0.969
Tsac_0682
KEGG: txy:Thexy_0113 hydrogenase accessory protein HypB; TIGRFAM: Hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like.
   
 
 0.894
hypA
Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
 
 0.837
Tsac_0684
KEGG: txy:Thexy_0115 hydrogenase assembly chaperone HypC/HupF; TIGRFAM: Hydrogenase expression/formation protein, HupF/HypC; PFAM: Hydrogenase expression/formation protein, HupF/HypC.
   
 
 0.787
Tsac_0683
KEGG: txy:Thexy_0114 acylphosphatase; TIGRFAM: Hydrogenase maturation factor, HypF-type; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type.
     
 0.773
Tsac_2126
KEGG: txy:Thexy_1580 hydrogenase, Fe-only; TIGRFAM: Iron hydrogenase, subset; PFAM: Iron hydrogenase, large subunit, C-terminal; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; Iron hydrogenase, small subunit-like.
  
 
 0.758
Your Current Organism:
Thermoanaerobacterium saccharolyticum
NCBI taxonomy Id: 1094508
Other names: T. saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum str. JW/SL-YS485, Thermoanaerobacterium saccharolyticum strain JW/SL-YS485, Thermoanaerobacterium sp. (strain JW/SL YS485)
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