STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tsac_0862PFAM: TRAG protein; KEGG: tbo:Thebr_0055 TRAG family protein. (603 aa)    
Predicted Functional Partners:
Tsac_0861
KEGG: tmt:Tmath_0077 hypothetical protein.
 
     0.952
Tsac_0867
KEGG: tbo:Thebr_0063 type IV secretory pathway VirB4 components-like protein.
 
  
 0.948
Tsac_0866
KEGG: tmt:Tmath_0082 hypothetical protein.
 
    0.904
Tsac_0860
KEGG: tmt:Tmath_0076 hypothetical protein.
       0.785
Tsac_0856
KEGG: toc:Toce_0421 plasmid segregation actin-type ATPase ParM.
 
     0.754
Tsac_0863
KEGG: tbo:Thebr_0056 hypothetical protein.
       0.751
Tsac_2429
PFAM: HNH endonuclease; KEGG: pjd:Pjdr2_1538 HNH endonuclease.
   
 
 0.713
Tsac_0864
KEGG: tbo:Thebr_0057 hypothetical protein.
       0.656
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
    
 0.625
Tsac_0868
PFAM: Peptidase M23; KEGG: tmt:Tmath_0084 peptidase M23.
       0.613
Your Current Organism:
Thermoanaerobacterium saccharolyticum
NCBI taxonomy Id: 1094508
Other names: T. saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum str. JW/SL-YS485, Thermoanaerobacterium saccharolyticum strain JW/SL-YS485, Thermoanaerobacterium sp. (strain JW/SL YS485)
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