STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tsac_1657PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; KEGG: cth:Cthe_2539 UBA/ThiF-type NAD/FAD binding fold. (273 aa)    
Predicted Functional Partners:
Tsac_1656
KEGG: cki:Calkr_1168 thiamine biosynthesis protein this; TIGRFAM: ThiS, thiamine-biosynthesis; PFAM: ThiamineS.
 
 
 0.993
Tsac_1658
KEGG: csc:Csac_1636 Mov34/MPN/PAD-1 family protein; PFAM: Mov34/MPN/PAD-1; SMART: Mov34/MPN/PAD-1.
 
 
 0.973
Tsac_1659
PFAM: SirA-like; KEGG: cth:Cthe_2542 SirA-like protein; Belongs to the sulfur carrier protein TusA family.
 
   
 0.946
Tsac_1655
PFAM: Nitrite/sulphite reductase 4Fe-4S region; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: ctc:CTC01213 anaerobic sulfite reductase subunit C; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
    0.885
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
  
 0.825
Tsac_0810
KEGG: txy:Thexy_0211 CoA-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; SirA-like; Sulphur relay, DsrE-like protein; SMART: Rhodanese-like; Belongs to the sulfur carrier protein TusA family.
  
  
 0.790
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.718
Tsac_1660
PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; KEGG: sgy:Sgly_0513 cysteine synthase.
  
    0.716
Tsac_2248
KEGG: txy:Thexy_1002 phosphomethylpyrimidine kinase; TIGRFAM: Phosphomethylpyrimidine kinase type-2; PFAM: Phosphomethylpyrimidine kinase type-1.
 
  
 0.672
hemL
TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; HAMAP: Glutamate-1-semialdehyde 2,1-aminomutase; KEGG: tmt:Tmath_0437 glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III.
  
  
 0.668
Your Current Organism:
Thermoanaerobacterium saccharolyticum
NCBI taxonomy Id: 1094508
Other names: T. saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum str. JW/SL-YS485, Thermoanaerobacterium saccharolyticum strain JW/SL-YS485, Thermoanaerobacterium sp. (strain JW/SL YS485)
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