STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tsac_1900KEGG: txy:Thexy_1213 stage V sporulation protein AD; TIGRFAM: Stage V sporulation AD; PFAM: Stage V sporulation AD. (337 aa)    
Predicted Functional Partners:
Tsac_1901
KEGG: txy:Thexy_1212 stage V sporulation protein AC; TIGRFAM: Sporulation stage V, protein AC; PFAM: SpoVA.
 
  
 0.990
Tsac_1899
KEGG: txy:Thexy_1214 stage V sporulation protein AE; TIGRFAM: Sporulation stage V, protein AE; PFAM: SpoVA.
 
  
 0.978
gpr
Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
  
 0.912
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
  
 0.904
Tsac_1904
KEGG: txy:Thexy_1209 RNA polymerase, sigma 28 subunit, SigF; TIGRFAM: RNA polymerase sigma-F type; RNA polymerase sigma-B/F/G type; RNA polymerase sigma-70; PFAM: RNA polymerase sigma-70 region 4; RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 3; Belongs to the sigma-70 factor family.
 
     0.863
Tsac_1917
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
 
   
 0.855
Tsac_1906
KEGG: txy:Thexy_1207 anti-sigma-factor antagonist; TIGRFAM: Anti-sigma F factor antagonist; Anti-sigma factor antagonist; PFAM: Sulphate transporter/antisigma-factor antagonist STAS.
 
   
 0.810
Tsac_1918
TIGRFAM: Peptidase S55, sporulation stage IV, protein B; PFAM: Peptidase S55, SpoIVB; KEGG: txy:Thexy_1195 stage IV sporulation protein B; SMART: PDZ/DHR/GLGF.
 
    0.807
Tsac_0744
Transcriptional regulator, AbrB family; KEGG: txy:Thexy_0155 stage V sporulation protein T; TIGRFAM: Sporulation stage V, protein T; Transcription regulator AbrB; PFAM: Transcription regulator AbrB/SpoV, predicted.
  
   
 0.803
Tsac_0752
PFAM: Bacillus/Clostridium GerA spore germination protein; KEGG: txy:Thexy_0163 GerA spore germination protein.
  
  
 0.794
Your Current Organism:
Thermoanaerobacterium saccharolyticum
NCBI taxonomy Id: 1094508
Other names: T. saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum str. JW/SL-YS485, Thermoanaerobacterium saccharolyticum strain JW/SL-YS485, Thermoanaerobacterium sp. (strain JW/SL YS485)
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