STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tsac_1990KEGG: txy:Thexy_1451 BadM/Rrf2 family transcriptional regulator; TIGRFAM: Transcriptional regulator, Rrf2; PFAM: Transcriptional regulator, Rrf2. (149 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
 0.956
Tsac_0395
KEGG: txy:Thexy_2292 SUF system FeS assembly protein, NifU family; TIGRFAM: SUF system FeS cluster assembly, SufU scaffold; PFAM: NIF system FeS cluster assembly, NifU, N-terminal.
 
  
 0.803
Tsac_1554
PFAM: Aminotransferase, class V/Cysteine desulfurase; KEGG: txy:Thexy_1049 Cysteine desulfurase.
 
  
 0.745
Tsac_0810
KEGG: txy:Thexy_0211 CoA-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; SirA-like; Sulphur relay, DsrE-like protein; SMART: Rhodanese-like; Belongs to the sulfur carrier protein TusA family.
  
  
 0.723
Tsac_1991
AAA ATPase central domain protein; KEGG: txy:Thexy_1452 ATPase AAA; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core.
       0.603
Tsac_1782
KEGG: txy:Thexy_1331 flagellar motor switch protein FliG; TIGRFAM: Flagellar motor switch protein FliG; PFAM: Flagellar motor switch protein FliG.
   
   0.534
Tsac_0411
KEGG: txy:Thexy_2311 glutaredoxin-like protein, YruB-family; TIGRFAM: Glutaredoxin-like protein, YruB; PFAM: Glutaredoxin.
 
  
 0.450
mnmA
tRNA-specific 2-thiouridylase mnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
  
 0.443
birA
BirA bifunctional protein, biotin operon repressor, biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
  
 0.427
Tsac_0256
PFAM: NADH:flavin oxidoreductase/NADH oxidase, N-terminal; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: txy:Thexy_2131 2,4-dienoyl-CoA reductase (NADPH).
  
  
 0.420
Your Current Organism:
Thermoanaerobacterium saccharolyticum
NCBI taxonomy Id: 1094508
Other names: T. saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum JW/SL-YS485, Thermoanaerobacterium saccharolyticum str. JW/SL-YS485, Thermoanaerobacterium saccharolyticum strain JW/SL-YS485, Thermoanaerobacterium sp. (strain JW/SL YS485)
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