node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | G4Z3E9_PHYSP | G4YIQ1 | G4Z3E9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.541 |
FEN1 | G4Z503_PHYSP | G4YIQ1 | G4Z503 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.999 |
FEN1 | G4ZN91_PHYSP | G4YIQ1 | G4ZN91 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | ENDO3c domain-containing protein. | 0.536 |
FEN1 | G5A9W5_PHYSP | G4YIQ1 | G5A9W5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | 0.499 |
FEN1 | G5AIC7_PHYSP | G4YIQ1 | G5AIC7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA_ligase_A_N domain-containing protein. | 0.963 |
FEN1 | NTH1 | G4YIQ1 | G4YS20 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. | 0.536 |
G4YTJ7_PHYSP | G4YTL3_PHYSP | G4YTJ7 | G4YTL3 | Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. | Sm domain-containing protein. | 0.999 |
G4YTJ7_PHYSP | G4Z3E9_PHYSP | G4YTJ7 | G4Z3E9 | Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. | Uncharacterized protein. | 0.484 |
G4YTJ7_PHYSP | G4ZR13_PHYSP | G4YTJ7 | G4ZR13 | Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. | Small nuclear ribonucleoprotein Sm D3. | 0.999 |
G4YTJ7_PHYSP | G4ZU34_PHYSP | G4YTJ7 | G4ZU34 | Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. | Sm domain-containing protein. | 0.999 |
G4YTL3_PHYSP | G4YTJ7_PHYSP | G4YTL3 | G4YTJ7 | Sm domain-containing protein. | Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. | 0.999 |
G4YTL3_PHYSP | G4Z3E9_PHYSP | G4YTL3 | G4Z3E9 | Sm domain-containing protein. | Uncharacterized protein. | 0.501 |
G4YTL3_PHYSP | G4ZR13_PHYSP | G4YTL3 | G4ZR13 | Sm domain-containing protein. | Small nuclear ribonucleoprotein Sm D3. | 0.999 |
G4YTL3_PHYSP | G4ZU34_PHYSP | G4YTL3 | G4ZU34 | Sm domain-containing protein. | Sm domain-containing protein. | 0.999 |
G4Z3E9_PHYSP | FEN1 | G4Z3E9 | G4YIQ1 | Uncharacterized protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.541 |
G4Z3E9_PHYSP | G4YTJ7_PHYSP | G4Z3E9 | G4YTJ7 | Uncharacterized protein. | Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. | 0.484 |
G4Z3E9_PHYSP | G4YTL3_PHYSP | G4Z3E9 | G4YTL3 | Uncharacterized protein. | Sm domain-containing protein. | 0.501 |
G4Z3E9_PHYSP | G4Z503_PHYSP | G4Z3E9 | G4Z503 | Uncharacterized protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.592 |
G4Z3E9_PHYSP | G4ZN91_PHYSP | G4Z3E9 | G4ZN91 | Uncharacterized protein. | ENDO3c domain-containing protein. | 0.523 |
G4Z3E9_PHYSP | G4ZR13_PHYSP | G4Z3E9 | G4ZR13 | Uncharacterized protein. | Small nuclear ribonucleoprotein Sm D3. | 0.527 |