node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EID32255.1 | EID32725.1 | HMPREF9969_0892 | HMPREF9969_0018 | Putative 3-deoxy-7-phosphoheptulonate synthase. | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.989 |
EID32255.1 | EID33340.1 | HMPREF9969_0892 | HMPREF9969_2225 | Putative 3-deoxy-7-phosphoheptulonate synthase. | Putative shikimate dehydrogenase. | 0.924 |
EID32255.1 | EID34317.1 | HMPREF9969_0892 | HMPREF9969_1207 | Putative 3-deoxy-7-phosphoheptulonate synthase. | Glutamine amidotransferase, class I. | 0.940 |
EID32255.1 | aroB | HMPREF9969_0892 | HMPREF9969_2163 | Putative 3-deoxy-7-phosphoheptulonate synthase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.977 |
EID32255.1 | aroC | HMPREF9969_0892 | HMPREF9969_2086 | Putative 3-deoxy-7-phosphoheptulonate synthase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.996 |
EID32255.1 | aroK | HMPREF9969_0892 | HMPREF9969_1079 | Putative 3-deoxy-7-phosphoheptulonate synthase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.954 |
EID32255.1 | aroQ | HMPREF9969_0892 | HMPREF9969_2278 | Putative 3-deoxy-7-phosphoheptulonate synthase. | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.758 |
EID32725.1 | EID32255.1 | HMPREF9969_0018 | HMPREF9969_0892 | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Putative 3-deoxy-7-phosphoheptulonate synthase. | 0.989 |
EID32725.1 | EID33340.1 | HMPREF9969_0018 | HMPREF9969_2225 | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Putative shikimate dehydrogenase. | 0.990 |
EID32725.1 | EID34317.1 | HMPREF9969_0018 | HMPREF9969_1207 | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Glutamine amidotransferase, class I. | 0.526 |
EID32725.1 | aroB | HMPREF9969_0018 | HMPREF9969_2163 | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.990 |
EID32725.1 | aroC | HMPREF9969_0018 | HMPREF9969_2086 | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.995 |
EID32725.1 | aroK | HMPREF9969_0018 | HMPREF9969_1079 | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.985 |
EID32725.1 | aroQ | HMPREF9969_0018 | HMPREF9969_2278 | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.577 |
EID32875.1 | aroK | HMPREF9969_1081 | HMPREF9969_1079 | NADH pyrophosphatase zinc ribbon domain / NUDIX domain multi-domain protein. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.605 |
EID32875.1 | speA | HMPREF9969_1081 | HMPREF9969_1078 | NADH pyrophosphatase zinc ribbon domain / NUDIX domain multi-domain protein. | Arginine 2-monooxygenase; Catalyzes the biosynthesis of agmatine from arginine. | 0.458 |
EID32875.1 | topA | HMPREF9969_1081 | HMPREF9969_1080 | NADH pyrophosphatase zinc ribbon domain / NUDIX domain multi-domain protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.694 |
EID33340.1 | EID32255.1 | HMPREF9969_2225 | HMPREF9969_0892 | Putative shikimate dehydrogenase. | Putative 3-deoxy-7-phosphoheptulonate synthase. | 0.924 |
EID33340.1 | EID32725.1 | HMPREF9969_2225 | HMPREF9969_0018 | Putative shikimate dehydrogenase. | Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.990 |
EID33340.1 | EID34317.1 | HMPREF9969_2225 | HMPREF9969_1207 | Putative shikimate dehydrogenase. | Glutamine amidotransferase, class I. | 0.882 |