STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
sucDsuccinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)    
Predicted Functional Partners:
SDJ89318.1
NADH dehydrogenase subunit C /NADH dehydrogenase subunit D.
  
 
 0.999
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
SDJ61289.1
2-oxoacid dehydrogenases acyltransferase (catalytic domain).
  
 0.997
SDL02310.1
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
 
 0.997
SDJ94228.1
Succinate dehydrogenase subunit B.
 0.996
SDJ94295.1
Succinate dehydrogenase subunit C.
  
 
 0.991
SDJ94198.1
Succinate dehydrogenase / fumarate reductase flavoprotein subunit.
 0.988
SDJ94527.1
Succinate dehydrogenase subunit A.
 0.987
SDJ94263.1
Succinate dehydrogenase subunit D.
  
 
 0.967
SDK56379.1
succinyl-CoA:acetate CoA-transferase.
   
 0.955
Your Current Organism:
Natronorubrum texcoconense
NCBI taxonomy Id: 1095776
Other names: CECT 8067, DSM 25211, JCM 17497, N. texcoconense, Natronorubrum sp. B4, Natronorubrum texcoconense Ruiz-Romero et al. 2013, strain B4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.