STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TAPDE_001024RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (794 aa)    
Predicted Functional Partners:
TAPDE_003576
Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.
   
 0.992
TAPDE_000112
DNA-directed RNA polymerase II subunit RPB3.
    
 0.978
TAPDE_003291
DNA-directed RNA polymerase II subunit RPB7.
    
 0.975
TAPDE_004003
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.971
TAPDE_005245
Uncharacterized protein.
    
 0.959
TAPDE_001923
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.954
TAPDE_002660
Uncharacterized protein.
    
 0.954
TAPDE_000357
DNA-directed RNA polymerase II complex subunit Rpb11.
    
 0.947
TAPDE_003355
Uncharacterized protein.
    
 0.934
TAPDE_003543
Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.
    
 0.891
Your Current Organism:
Taphrina deformans
NCBI taxonomy Id: 1097556
Other names: T. deformans PYCC 5710, Taphrina deformans CBS 356.35, Taphrina deformans PYCC 5710
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.