STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A507DRV7Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (340 aa)    
Predicted Functional Partners:
PHI929
Succinate-CoA ligase subunit beta.
 0.999
A0A507E8M2
CoA_binding domain-containing protein.
  
0.993
A0A507E4I7
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
 
 0.986
KGD1-2
Oxoglutarate dehydrogenase (Succinyl-transferring).
 
 0.981
A0A507EFR1
Uncharacterized protein.
  
 
 0.978
KGD1
Oxoglutarate dehydrogenase (Succinyl-transferring).
 
 0.970
A0A507EBS5
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
 
 0.966
KGD2
Dihydrolipoyllysine-residue succinyltransferase.
 
 0.959
FUM1
Fumarate hydratase.
  
 0.954
A0A507EAV7
Cytochrome b5 heme-binding domain-containing protein.
  
 0.943
Your Current Organism:
Powellomyces hirtus
NCBI taxonomy Id: 109895
Other names: P. hirtus
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