STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A507DX36Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (409 aa)    
Predicted Functional Partners:
A0A507EFG5
Autophagy-related protein.
   
 0.997
A0A507DW21
Protein kinase domain-containing protein.
   
 
 0.975
A0A507DY35
Lipase_3 domain-containing protein.
   
 
 0.967
A0A507EAQ9
Protein kinase domain-containing protein.
   
 
 0.900
A0A507EDP1
Lipase_3 domain-containing protein.
   
 
 0.871
A0A507EEU1
Autophagy-related protein 3.
   
 
 0.776
A0A507E776
Uncharacterized protein.
   
 
 0.740
A0A507EEV2
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
   
 
 0.688
A0A507E3Z5
Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily.
   
 
 0.641
A0A507EB00
Uncharacterized protein.
    
 
 0.608
Your Current Organism:
Powellomyces hirtus
NCBI taxonomy Id: 109895
Other names: P. hirtus
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