STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A507EI46Uncharacterized protein. (3488 aa)    
Predicted Functional Partners:
A0A507EFH7
Uncharacterized protein.
   
 0.912
CDC21
Thymidylate synthase.
  
 
 0.761
A0A507E8T7
S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 
  0.714
A0A507DZK0
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
    
 0.648
CDC8
dTMP kinase.
    
 0.635
A0A507EEI4
DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.
  
 
 0.614
RIB1
GTP cyclohydrolase II.
    
 0.603
RIB3
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
    
 0.603
GLO1
Lactoylglutathione lyase.
   
 
 0.598
A0A507DU62
Uncharacterized protein.
   
 
 0.598
Your Current Organism:
Powellomyces hirtus
NCBI taxonomy Id: 109895
Other names: P. hirtus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.