node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EUJ10898.1 | EUJ11288.1 | Meth11DRAFT_1729 | Meth11DRAFT_2128 | Molecular chaperone; IMG reference gene:2512647984; PFAM: Hsp70 protein; Belongs to the heat shock protein 70 family. | Hypothetical protein; IMG reference gene:2512648383; PFAM: TPR repeat. | 0.803 |
EUJ10898.1 | clpB | Meth11DRAFT_1729 | Meth11DRAFT_0605 | Molecular chaperone; IMG reference gene:2512647984; PFAM: Hsp70 protein; Belongs to the heat shock protein 70 family. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.967 |
EUJ10898.1 | clpP | Meth11DRAFT_1729 | Meth11DRAFT_1366 | Molecular chaperone; IMG reference gene:2512647984; PFAM: Hsp70 protein; Belongs to the heat shock protein 70 family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.737 |
EUJ10898.1 | dnaJ | Meth11DRAFT_1729 | Meth11DRAFT_1947 | Molecular chaperone; IMG reference gene:2512647984; PFAM: Hsp70 protein; Belongs to the heat shock protein 70 family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.998 |
EUJ10898.1 | groS | Meth11DRAFT_1729 | Meth11DRAFT_0456 | Molecular chaperone; IMG reference gene:2512647984; PFAM: Hsp70 protein; Belongs to the heat shock protein 70 family. | Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.896 |
EUJ10898.1 | grpE | Meth11DRAFT_1729 | Meth11DRAFT_1945 | Molecular chaperone; IMG reference gene:2512647984; PFAM: Hsp70 protein; Belongs to the heat shock protein 70 family. | Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...] | 0.989 |
EUJ10898.1 | hscA | Meth11DRAFT_1729 | Meth11DRAFT_1880 | Molecular chaperone; IMG reference gene:2512647984; PFAM: Hsp70 protein; Belongs to the heat shock protein 70 family. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.595 |
EUJ10898.1 | htpG | Meth11DRAFT_1729 | Meth11DRAFT_0808 | Molecular chaperone; IMG reference gene:2512647984; PFAM: Hsp70 protein; Belongs to the heat shock protein 70 family. | Molecular chaperone of HSP90 family; Molecular chaperone. Has ATPase activity. | 0.994 |
EUJ11288.1 | EUJ10898.1 | Meth11DRAFT_2128 | Meth11DRAFT_1729 | Hypothetical protein; IMG reference gene:2512648383; PFAM: TPR repeat. | Molecular chaperone; IMG reference gene:2512647984; PFAM: Hsp70 protein; Belongs to the heat shock protein 70 family. | 0.803 |
EUJ11288.1 | clpB | Meth11DRAFT_2128 | Meth11DRAFT_0605 | Hypothetical protein; IMG reference gene:2512648383; PFAM: TPR repeat. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.988 |
EUJ11288.1 | clpP | Meth11DRAFT_2128 | Meth11DRAFT_1366 | Hypothetical protein; IMG reference gene:2512648383; PFAM: TPR repeat. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.814 |
EUJ11288.1 | dnaJ | Meth11DRAFT_2128 | Meth11DRAFT_1947 | Hypothetical protein; IMG reference gene:2512648383; PFAM: TPR repeat. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.999 |
EUJ11288.1 | dnaK | Meth11DRAFT_2128 | Meth11DRAFT_1946 | Hypothetical protein; IMG reference gene:2512648383; PFAM: TPR repeat. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.803 |
EUJ11288.1 | groS | Meth11DRAFT_2128 | Meth11DRAFT_0456 | Hypothetical protein; IMG reference gene:2512648383; PFAM: TPR repeat. | Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.935 |
EUJ11288.1 | grpE | Meth11DRAFT_2128 | Meth11DRAFT_1945 | Hypothetical protein; IMG reference gene:2512648383; PFAM: TPR repeat. | Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...] | 0.984 |
EUJ11288.1 | hscA | Meth11DRAFT_2128 | Meth11DRAFT_1880 | Hypothetical protein; IMG reference gene:2512648383; PFAM: TPR repeat. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.803 |
EUJ11288.1 | htpG | Meth11DRAFT_2128 | Meth11DRAFT_0808 | Hypothetical protein; IMG reference gene:2512648383; PFAM: TPR repeat. | Molecular chaperone of HSP90 family; Molecular chaperone. Has ATPase activity. | 0.999 |
clpB | EUJ10898.1 | Meth11DRAFT_0605 | Meth11DRAFT_1729 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Molecular chaperone; IMG reference gene:2512647984; PFAM: Hsp70 protein; Belongs to the heat shock protein 70 family. | 0.967 |
clpB | EUJ11288.1 | Meth11DRAFT_0605 | Meth11DRAFT_2128 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Hypothetical protein; IMG reference gene:2512648383; PFAM: TPR repeat. | 0.988 |
clpB | clpP | Meth11DRAFT_0605 | Meth11DRAFT_1366 | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.984 |