Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CF8_0178LacI family transcription regulator. (338 aa)    
Predicted Functional Partners:
CF8_3263
PTS system glucose-like transporter subunit IIB.
  
 
 0.918
CF8_2503
Glutamate synthase (NADH) large subunit.
    
 
 0.884
CF8_2802
HPr family phosphocarrier protein.
 
 
 
 0.853
CF8_2195
Thioredoxin reductase.
    
 
 0.759
CF8_0355
Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.742
CF8_3329
Hypothetical protein.
    
 0.718
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.709
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
   0.709
CF8_0179
Extracellular solute-binding protein.
 
  
 0.686
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.676
Your Current Organism:
Nocardioides sp. CF8
NCBI taxonomy Id: 110319
Other names: N. sp. CF8
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